AC   MF_00586;
DC   Protein; auto
TR   HAMAP; MF_00586; -; 1; level=0
XX
Names: GatD
XX
ID   GATD
DE   RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit D;
DE            Short=Glu-ADT subunit D;
DE            EC=6.3.5.-;
GN   Name=gatD;
XX
CC   -!- FUNCTION: Allows the formation of correctly charged Gln-tRNA(Gln)
CC       through the transamidation of misacylated Glu-tRNA(Gln) in organisms
CC       which lack glutaminyl-tRNA synthetase. The reaction takes place in the
CC       presence of glutamine and ATP through an activated gamma-phospho-Glu-
CC       tRNA(Gln). The GatDE system is specific for glutamate and does not act
CC       on aspartate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) +
CC         L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate;
CC         Xref=Rhea:RHEA:17521, Rhea:RHEA-COMP:9681, Rhea:RHEA-COMP:9684,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58359,
CC         ChEBI:CHEBI:78520, ChEBI:CHEBI:78521, ChEBI:CHEBI:456216;
CC   -!- SUBUNIT: Heterodimer of GatD and GatE.
CC   -!- SIMILARITY: Belongs to the asparaginase 1 family. GatD subfamily.
XX
DR   Pfam; PF00710; Asparaginase; 1; trigger=no
DR   PRINTS; PR00139; ASNGLNASE; 1; trigger=no
DR   NCBIfam; TIGR00519; AsnASE_I; 1; trigger=no
DR   NCBIfam; TIGR02153; gatD_arch; 1; trigger=no
DR   PROSITE; PS00144; ASN_GLN_ASE_1; 1; trigger=no
DR   PROSITE; PS00917; ASN_GLN_ASE_2; 1; trigger=no
DR   PROSITE; PS51732; ASN_GLN_ASE_3; 1; trigger=yes
XX
KW   ATP-binding
KW   Ligase
KW   Nucleotide-binding
KW   Protein biosynthesis
XX
GO   GO:0050567; F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
GO   GO:0006412; P:translation
XX
FT   From: GATD_METTH (O26802)
FT   ACT_SITE        101
FT   Condition: T
FT   ACT_SITE        177
FT   Condition: T
FT   ACT_SITE        178
FT   Condition: D
FT   ACT_SITE        254
FT   Condition: K
XX
Size: 406-458;
Related: None;
Template: O26802;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.24 2023/06/01
//