AC   MF_00592;
DC   Protein; auto
TR   HAMAP; MF_00592; -; 1; level=0
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Names: DeoC_type2
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ID   DEOC
DE   RecName: Full=Deoxyribose-phosphate aldolase;
DE            Short=DERA;
DE            EC=4.1.2.4;
DE   AltName: Full=2-deoxy-D-ribose 5-phosphate aldolase;
DE   AltName: Full=Phosphodeoxyriboaldolase;
DE            Short=Deoxyriboaldolase;
GN   Name=deoC;
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CC   -!- FUNCTION: Catalyzes a reversible aldol reaction between acetaldehyde
CC       and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-
CC       phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde
CC         3-phosphate; Xref=Rhea:RHEA:12821, ChEBI:CHEBI:15343,
CC         ChEBI:CHEBI:59776, ChEBI:CHEBI:62877; EC=4.1.2.4;
CC   -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC       degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC       deoxy-alpha-D-ribose 1-phosphate: step 2/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family. DeoC type 2
CC       subfamily.
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DR   Pfam; PF01791; DeoC; 1; trigger=no
DR   NCBIfam; TIGR00126; deoC; 1; trigger=no
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KW   Cytoplasm
KW   Lyase
KW   Schiff base
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GO   GO:0004139; F:deoxyribose-phosphate aldolase activity
GO   GO:0006018; P:2-deoxyribose 1-phosphate catabolic process
GO   GO:0005737; C:cytoplasm
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FT   From: DEOC_ECOLI (P0A6L0)
FT   ACT_SITE        102
FT                   /note="Proton donor/acceptor"
FT   Condition: [DE]
FT   ACT_SITE        167
FT                   /note="Schiff-base intermediate with acetaldehyde"
FT   Condition: K
FT   ACT_SITE        201
FT                   /note="Proton donor/acceptor"
FT   Condition: K
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Size: 210-325;
Related: MF_00114;
Template: P0A6L0; Q8ZJV8;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.35 2024/01/24
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