AC   MF_00601;
DC   Protein; auto
TR   HAMAP; MF_00601; -; 1; level=0
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Names: EutC
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ID   EUTC
case <OC:Bacteria>
DE   RecName: Full=Ethanolamine ammonia-lyase small subunit;
DE            Short=EAL small subunit;
DE            EC=4.3.1.7;
else case <OC:Archaea>
DE   RecName: Full=Putative ethanolamine ammonia-lyase small subunit;
DE            Short=EAL small subunit;
DE            EC=4.3.1.7;
end case
GN   Name=eutC;
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case <OC:Bacteria>
CC   -!- FUNCTION: Catalyzes the deamination of various vicinal amino-alcohols
CC       to oxo compounds. Allows this organism to utilize ethanolamine as the
CC       sole source of nitrogen and carbon in the presence of external vitamin
CC       B12.
else case <OC:Archaea>
CC   -!- FUNCTION: May catalyze the deamination of various vicinal amino-
CC       alcohols to oxo compounds.Would allow this organism to utilize
CC       ethanolamine as the sole source of nitrogen and carbon in the presence
CC       of external vitamin B12.
end case
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ethanolamine = acetaldehyde + NH4(+); Xref=Rhea:RHEA:15313,
CC         ChEBI:CHEBI:15343, ChEBI:CHEBI:28938, ChEBI:CHEBI:57603; EC=4.3.1.7;
CC   -!- COFACTOR:
CC       Name=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408;
CC       Note=Binds between the large and small subunits.
CC   -!- PATHWAY: Amine and polyamine degradation; ethanolamine degradation.
CC   -!- SUBUNIT: The basic unit is a heterodimer which dimerizes to form
CC       tetramers. The heterotetramers trimerize; 6 large subunits form a core
CC       ring with 6 small subunits projecting outwards.
case <OC:Bacteria>
CC   -!- SUBCELLULAR LOCATION: Bacterial microcompartment.
end case
CC   -!- SIMILARITY: Belongs to the EutC family.
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DR   Pfam; PF05985; EutC; 1; trigger=no
DR   PIRSF; PIRSF018982; EutC; 1; trigger=no
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KW   Lyase
KW   Cobalt
KW   Cobalamin
case <OC:Bacteria>
KW   Bacterial microcompartment
end case
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GO   GO:0008851; F:ethanolamine ammonia-lyase activity
GO   GO:0009350; C:ethanolamine ammonia-lyase complex
GO   GO:0046336; P:ethanolamine catabolic process
GO   GO:0031419; F:cobalamin binding
case <OC:Bacteria>
GO   GO:0031471; C:ethanolamine degradation polyhedral organelle
end case
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FT   From: EUTC_ECOLI (P19636)
FT   BINDING         207
FT                   /ligand="adenosylcob(III)alamin"
FT                   /ligand_id="ChEBI:CHEBI:18408"
FT   Condition: V
FT   BINDING         228
FT                   /ligand="adenosylcob(III)alamin"
FT                   /ligand_id="ChEBI:CHEBI:18408"
FT   Condition: E
case not <OC:Bacillota>
FT   BINDING         258
FT                   /ligand="adenosylcob(III)alamin"
FT                   /ligand_id="ChEBI:CHEBI:18408"
FT   Condition: C
end case
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Size: 235-330;
Related: None;
Template: P19265; P19636;
Scope:
 Bacteria
 Archaea; Halobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: Both large and small subunits are found in Archaeal Halobacteria.
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# Revision 1.25 2023/01/13
//