AC   MF_00608;
DC   Protein; auto
TR   HAMAP; MF_00608; -; 1; level=0
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Names: GTP_cyclohydro_3
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ID   GCH3
DE   RecName: Full=GTP cyclohydrolase III;
DE            EC=3.5.4.29;
GN   Name=gch3;
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CC   -!- FUNCTION: Catalyzes the formation of 2-amino-5-formylamino-6-
CC       ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and
CC       inorganic phosphate from GTP. Also has an independent pyrophosphate
CC       phosphohydrolase activity.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-
CC         ribosylamino)pyrimidin-4(3H)-one + 2 H(+) + 2 phosphate;
CC         Xref=Rhea:RHEA:22468, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:57258; EC=3.5.4.29;
CC   -!- SIMILARITY: Belongs to the archaeal-type GTP cyclohydrolase family.
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DR   Pfam; PF05165; GGDN; 1; trigger=no
DR   PIRSF; PIRSF009265; GTP_cyclohydro_3; 1; trigger=no
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KW   GTP-binding
KW   Hydrolase
KW   Nucleotide-binding
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GO   GO:0016814; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
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FT   None
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Size: 221-268;
Related: None;
Template: Q57609;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in HALSA
Plasmid: None
Comments: None
XX
# Revision 1.25 2019/11/18
//