AC   MF_00617;
DC   Protein; auto
TR   HAMAP; MF_00617; -; 1; level=0
XX
Names: MPGP_rel
XX
ID   MPGP
DE   RecName: Full=Mannosyl-3-phosphoglycerate phosphatase;
DE            Short=MPGP;
DE            EC=3.1.3.70;
case <OC:Archaea>
GN   Name=mngB;
end case
XX
case <OC:Archaea>
CC   -!- FUNCTION: Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the
CC       osmolyte mannosylglycerate (MG).
CC   -!- PATHWAY: Carbohydrate biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate
CC       biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate from GDP-alpha-D-mannose
CC       (MPG route): step 2/2.
end case
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-O-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = (2R)-2-O-
CC         (alpha-D-mannosyl)-glycerate + phosphate; Xref=Rhea:RHEA:19309,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:57541,
CC         ChEBI:CHEBI:57744; EC=3.1.3.70;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. MPGP family.
XX
DR   Pfam; PF08282; Hydrolase_3; 1; trigger=no
DR   NCBIfam; TIGR01484; HAD-SF-IIB; 1; trigger=no
DR   NCBIfam; TIGR01486; HAD-SF-IIB-MPGP; 1; trigger=no
DR   NCBIfam; TIGR02461; osmo_MPG_phos; 0-1; trigger=no
DR   NCBIfam; TIGR02463; MPGP_rel; 0-1; trigger=no
XX
KW   Cytoplasm
KW   Hydrolase
KW   Magnesium
KW   Metal-binding
XX
GO   GO:0050531; F:mannosyl-3-phosphoglycerate phosphatase activity
GO   GO:0005737; C:cytoplasm
XX
FT   From: MPGP_PYRHO (O58690)
FT   ACT_SITE        8
FT                   /note="Nucleophile"
FT   Condition: D
FT   BINDING         8
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
FT   BINDING         10
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
FT   BINDING         169
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Optional; Condition: S
FT   BINDING         204
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
XX
Size: 242-281;
Related: None;
Template: O58690; P76329;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.31 2023/06/01
//