AC   MF_00626;
DC   Protein; auto
TR   HAMAP; MF_00626; -; 1; level=0
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Names: Germination_prot
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ID   GPR
DE   RecName: Full=Germination protease;
DE            EC=3.4.24.78;
DE   AltName: Full=GPR endopeptidase;
DE   AltName: Full=Germination proteinase;
DE   AltName: Full=Spore protease;
DE   Flags: Precursor;
GN   Name=gpr;
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CC   -!- FUNCTION: Initiates the rapid degradation of small, acid-soluble
CC       proteins during spore germination.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endopeptidase action with P4 Glu or Asp, P1 preferably Glu >
CC         Asp, P1' hydrophobic and P2' Ala.; EC=3.4.24.78;
CC   -!- SUBUNIT: Homotetramer.
CC   -!- PTM: Autoproteolytically processed. The inactive tetrameric zymogen
CC       termed p46 autoprocesses to a smaller form termed p41, which is active
CC       only during spore germination.
CC   -!- SIMILARITY: Belongs to the peptidase A25 family.
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DR   Pfam; PF03418; Peptidase_A25; 1; trigger=no
DR   PIRSF; PIRSF019549; Peptidase_A25; 1; trigger=no
DR   NCBIfam; TIGR01441; GPR; 1; trigger=no
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KW   Hydrolase
KW   Protease
KW   Zymogen
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GO   GO:0004222; F:metalloendopeptidase activity
GO   GO:0006508; P:proteolysis
GO   GO:0009847; P:spore germination
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FT   From: GPR_PRIM1 (P22321)
FT   PROPEP          Nter..15
FT   CHAIN           16..Cter
FT                   /note="Germination protease"
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Size: 323-372;
Related: None;
Template: P22321;
Scope:
 Bacteria; Bacillales
 Bacteria; Clostridia
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.19 2023/06/01
//