AC   MF_00687;
DC   Protein; auto
TR   HAMAP; MF_00687; -; 1; level=0
XX
Names: KduI
XX
ID   KDUI
DE   RecName: Full=4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase;
DE            EC=5.3.1.17;
DE   AltName: Full=5-keto-4-deoxyuronate isomerase;
DE   AltName: Full=DKI isomerase;
GN   Name=kduI;
XX
CC   -!- FUNCTION: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-
CC       glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-
CC         hexodiulosonate; Xref=Rhea:RHEA:23896, ChEBI:CHEBI:17117,
CC         ChEBI:CHEBI:29071; EC=5.3.1.17;
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit.;
end case
CC   -!- PATHWAY: Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-
CC       gluconate from pectin: step 4/5.
case <OC:Escherichia>
CC   -!- SUBUNIT: Homohexamer.
end case
CC   -!- SIMILARITY: Belongs to the KduI family.
XX
DR   Pfam; PF04962; KduI; 1; trigger=no
XX
KW   Isomerase
case <FTGroup:1>
KW   Metal-binding
KW   Zinc
end case
XX
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
GO   GO:0008697; F:4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity
GO   GO:0045490; P:pectin catabolic process
XX
FT   From: KDUI_ECOLI (Q46938)
FT   BINDING         196
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
FT   BINDING         198
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
FT   BINDING         203
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: E
FT   BINDING         245
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
XX
Size: 274-292;
Related: None;
Template: Q46938; Q05529; P50843;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in BACTN, ENTFA, RHIME
Plasmid: in RHIME
Comments: None
XX
# Revision 1.26 2022/11/19
//