AC   MF_00689;
DC   Protein; auto
TR   HAMAP; MF_00689; -; 1; level=0
XX
Names: Bpt
XX
ID   BPT
DE   RecName: Full=Aspartate/glutamate leucyltransferase;
DE            EC=2.3.2.29;
GN   Name=bpt;
XX
CC   -!- FUNCTION: Functions in the N-end rule pathway of protein degradation
CC       where it conjugates Leu from its aminoacyl-tRNA to the N-termini of
CC       proteins containing an N-terminal aspartate or glutamate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = H(+) +
CC         N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu);
CC         Xref=Rhea:RHEA:50412, Rhea:RHEA-COMP:9613, Rhea:RHEA-COMP:9622,
CC         Rhea:RHEA-COMP:12664, Rhea:RHEA-COMP:12668, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:64721, ChEBI:CHEBI:78442, ChEBI:CHEBI:78494,
CC         ChEBI:CHEBI:133041; EC=2.3.2.29;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = H(+) +
CC         N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu);
CC         Xref=Rhea:RHEA:50420, Rhea:RHEA-COMP:9613, Rhea:RHEA-COMP:9622,
CC         Rhea:RHEA-COMP:12669, Rhea:RHEA-COMP:12674, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:64720, ChEBI:CHEBI:78442, ChEBI:CHEBI:78494,
CC         ChEBI:CHEBI:133042; EC=2.3.2.29;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the R-transferase family. Bpt subfamily.
XX
DR   Pfam; PF04377; ATE_C; 1; trigger=no
DR   Pfam; PF04376; ATE_N; 1; trigger=no
DR   PIRSF; PIRSF037208; ATE_pro_prd; 1; trigger=no
XX
KW   Cytoplasm
KW   Transferase
KW   Acyltransferase
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GO   GO:0008914; F:leucyl-tRNA--protein transferase activity
GO   GO:0030163; P:protein catabolic process
GO   GO:0005737; C:cytoplasm
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FT   None
XX
Size: 200-325;
Related: None;
Template: Q8DAR7; Q8UG81; Q983E4;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.23 2023/07/28
//