AC   MF_00705;
DC   Protein; auto
TR   HAMAP; MF_00705; -; 1; level=0
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Names: IMP_cyclohydrol
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ID   PURO
DE   RecName: Full=IMP cyclohydrolase;
DE            EC=3.5.4.10;
DE   AltName: Full=IMP synthase;
DE   AltName: Full=Inosinicase;
GN   Name=purO;
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CC   -!- FUNCTION: Catalyzes the cyclization of 5-formylamidoimidazole-4-
CC       carboxamide ribonucleotide to IMP.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-
CC         carboxamide; Xref=Rhea:RHEA:18445, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:58053, ChEBI:CHEBI:58467; EC=3.5.4.10;
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway; IMP
CC       from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step
CC       1/1.
CC   -!- SIMILARITY: Belongs to the archaeal IMP cyclohydrolase family.
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DR   Pfam; PF07826; IMP_cyclohyd; 1; trigger=no
DR   PIRSF; PIRSF004866; IMP_cclhdr_arch; 1; trigger=no
DR   NCBIfam; TIGR01922; PurO_arch; 1; trigger=no
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KW   Purine biosynthesis
KW   Hydrolase
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GO   GO:0003937; F:IMP cyclohydrolase activity
GO   GO:0006189; P:'de novo' IMP biosynthetic process
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FT   None
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Size: 190-230;
Related: None;
Template: Q58043;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.24 2023/06/01
//