AC MF_00713; DC Protein; auto TR HAMAP; MF_00713; -; 1; level=0 XX Names: GcvPB XX ID GCSPB DE RecName: Full=Probable glycine dehydrogenase (decarboxylating) subunit 2; DE EC=1.4.4.2; DE AltName: Full=Glycine cleavage system P-protein subunit 2; DE AltName: Full=Glycine decarboxylase subunit 2; DE AltName: Full=Glycine dehydrogenase (aminomethyl-transferring) subunit 2; GN Name=gcvPB; XX CC -!- FUNCTION: The glycine cleavage system catalyzes the degradation of CC glycine. The P protein binds the alpha-amino group of glycine through CC its pyridoxal phosphate cofactor; CO(2) is released and the remaining CC methylamine moiety is then transferred to the lipoamide cofactor of the CC H protein. CC -!- CATALYTIC ACTIVITY: CC Reaction=glycine + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage CC complex H protein] = CO2 + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]- CC L-lysyl-[glycine-cleavage complex H protein]; Xref=Rhea:RHEA:24304, CC Rhea:RHEA-COMP:10494, Rhea:RHEA-COMP:10495, ChEBI:CHEBI:15378, CC ChEBI:CHEBI:16526, ChEBI:CHEBI:57305, ChEBI:CHEBI:83099, CC ChEBI:CHEBI:83143; EC=1.4.4.2; CC -!- COFACTOR: CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; CC -!- SUBUNIT: The glycine cleavage system is composed of four proteins: P, CC T, L and H. In this organism, the P 'protein' is a heterodimer of two CC subunits. CC -!- SIMILARITY: Belongs to the GcvP family. C-terminal subunit subfamily. XX DR Pfam; PF02347; GDC-P; 1; trigger=no XX KW Oxidoreductase KW Pyridoxal phosphate XX GO GO:0019464; P:glycine decarboxylation via glycine cleavage system XX FT From: GCSPB_BACSU (P54377) FT MOD_RES 273 FT /note="N6-(pyridoxal phosphate)lysine" FT Condition: K XX Size: 472-534; Related: MF_00711; Template: P54377; Scope: Bacteria Archaea Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: None XX # Revision 1.23 2023/09/14 //