AC   MF_00725;
DC   Protein; auto
TR   HAMAP; MF_00725; -; 1; level=0
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Names: FlhD
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ID   FLHD
DE   RecName: Full=Flagellar transcriptional regulator FlhD;
GN   Name=flhD;
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CC   -!- FUNCTION: Functions in complex with FlhC as a master transcriptional
CC       regulator that regulates transcription of several flagellar and non-
CC       flagellar operons by binding to their promoter region. Activates
CC       expression of class 2 flagellar genes, including fliA, which is a
CC       flagellum-specific sigma factor that turns on the class 3 genes. Also
CC       regulates genes whose products function in a variety of physiological
CC       pathways.
CC   -!- SUBUNIT: Homodimer; disulfide-linked. Forms a heterohexamer composed of
CC       two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming
CC       a heterotrimer, and a hexamer assembles by dimerization of two
CC       heterotrimers.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- DOMAIN: The C-terminal region contains a putative helix-turn-helix
CC       (HTH) motif, suggesting that this region may bind DNA.
CC   -!- SIMILARITY: Belongs to the FlhD family.
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DR   Pfam; PF05247; FlhD; 1; trigger=no
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KW   Activator
KW   Bacterial flagellum biogenesis
KW   Cytoplasm
case <FT:1>
KW   Disulfide bond
end case
KW   DNA-binding
KW   Transcription
KW   Transcription regulation
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GO   GO:0003677; F:DNA binding
GO   GO:0006355; P:regulation of DNA-templated transcription
GO   GO:1902208; P:regulation of bacterial-type flagellum assembly
GO   GO:0005737; C:cytoplasm
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FT   From: FLHD_ECOLI (P0A8S9)
FT   DISULFID        65
FT                   /note="Interchain"
FT   Condition: C
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Size: 85-127;
Related: None;
Template: P0A8S9;
Scope:
 Bacteria; Pseudomonadota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: in RALN1, RALP1
Comments: None
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# Revision 1.27 2023/11/28
//