AC   MF_00731;
DC   Protein; auto
TR   HAMAP; MF_00731; -; 1; level=0
XX
Names: MenE
XX
ID   MENE
DE   RecName: Full=2-succinylbenzoate--CoA ligase;
DE            EC=6.2.1.26;
DE   AltName: Full=o-succinylbenzoyl-CoA synthetase;
DE            Short=OSB-CoA synthetase;
GN   Name=menE;
XX
CC   -!- FUNCTION: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA
CC       (OSB-CoA).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP +
CC         diphosphate; Xref=Rhea:RHEA:17009, ChEBI:CHEBI:18325,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57364, ChEBI:CHEBI:456215; EC=6.2.1.26;
CC   -!- PATHWAY: Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate
CC       biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 5/7.
case not <OC:Cyanobacteriota>
CC   -!- PATHWAY: Quinol/quinone metabolism; menaquinone biosynthesis.
else case <OC:Cyanobacteriota>
CC   -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
end case
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       MenE subfamily.
XX
DR   Pfam; PF00501; AMP-binding; 1; trigger=no
DR   Pfam; PF13193; AMP-binding_C; 1; trigger=no
DR   NCBIfam; TIGR01923; MenE; 1; trigger=no
DR   PROSITE; PS00455; AMP_BINDING; 1; trigger=no
XX
KW   ATP-binding
KW   Ligase
case not <OC:Cyanobacteriota>
KW   Menaquinone biosynthesis
end case
KW   Nucleotide-binding
XX
GO   GO:0008756; F:o-succinylbenzoate-CoA ligase activity
case not <OC:Cyanobacteriota>
GO   GO:0009234; P:menaquinone biosynthetic process
else case <OC:Cyanobacteriota>
GO   GO:0042372; P:phylloquinone biosynthetic process
end case
XX
FT   None
XX
Size: 438-514;
Related: None;
Template: P23971;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in STAAU
Plasmid: None
Comments: None
XX
# Revision 1.29 2023/06/01
//