AC   MF_00740;
DC   Protein; auto
TR   HAMAP; MF_00740; -; 1; level=0
XX
Names: Phosphopentomut
XX
ID   DEOB
DE   RecName: Full=Phosphopentomutase;
DE            EC=5.4.2.7;
DE   AltName: Full=Phosphodeoxyribomutase;
GN   Name=deoB;
XX
CC   -!- FUNCTION: Isomerase that catalyzes the conversion of deoxy-ribose 1-
CC       phosphate (dRib-1-P) and ribose 1-phosphate (Rib-1-P) to deoxy-ribose
CC       5-phosphate (dRib-5-P) and ribose 5-phosphate (Rib-5-P), respectively.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-
CC         phosphate; Xref=Rhea:RHEA:27658, ChEBI:CHEBI:57259,
CC         ChEBI:CHEBI:62877; EC=5.4.2.7;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-ribose 1-phosphate = D-ribose 5-phosphate;
CC         Xref=Rhea:RHEA:18793, ChEBI:CHEBI:57720, ChEBI:CHEBI:78346;
CC         EC=5.4.2.7;
case <FTGroup:1> and <FTGroup:2>
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC       Note=Binds 2 manganese ions.;
else
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
end case
CC   -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC       degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC       deoxy-alpha-D-ribose 1-phosphate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the phosphopentomutase family.
XX
DR   Pfam; PF01676; Metalloenzyme; 1; trigger=no
DR   NCBIfam; TIGR01696; deoB; 1; trigger=no
DR   PIRSF; PIRSF001491; Ppentomutase; 1; trigger=no
XX
KW   Cytoplasm
KW   Isomerase
KW   Metal-binding
KW   Manganese
XX
GO   GO:0030145; F:manganese ion binding
GO   GO:0008973; F:phosphopentomutase activity
GO   GO:0006018; P:2-deoxyribose 1-phosphate catabolic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: DEOB_STRMU (Q8DTU0)
FT   BINDING         13
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /ligand_label="1"
FT   Group: 1; Condition: D
FT   BINDING         298
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /ligand_label="2"
FT   Group: 2; Condition: D
FT   BINDING         303
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /ligand_label="2"
FT   Group: 2; Condition: H
FT   BINDING         339
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /ligand_label="1"
FT   Group: 1; Condition: D
FT   BINDING         340
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /ligand_label="1"
FT   Group: 1; Condition: H
FT   BINDING         351
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /ligand_label="2"
FT   Group: 2; Condition: H
XX
Size: 388-418;
Related: None;
Template: P0A6K6; Q8DTU0;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in STRA1
Plasmid: None
Comments: None
XX
# Revision 1.30 2024/01/24
//