AC   MF_00766;
DC   Protein; auto
TR   HAMAP; MF_00766; -; 1; level=0
XX
Names: PGT_MtgA
XX
ID   MTGA
DE   RecName: Full=Biosynthetic peptidoglycan transglycosylase;
DE            EC=2.4.1.129;
DE   AltName: Full=Glycan polymerase;
DE   AltName: Full=Peptidoglycan glycosyltransferase MtgA;
DE            Short=PGT;
GN   Name=mtgA;
XX
CC   -!- FUNCTION: Peptidoglycan polymerase that catalyzes glycan chain
CC       elongation from lipid-linked precursors.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-
CC         Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-
CC         (1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-
CC         cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-
CC         D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl
CC         diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+);
CC         Xref=Rhea:RHEA:23708, Rhea:RHEA-COMP:9602, Rhea:RHEA-COMP:9603,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:58405, ChEBI:CHEBI:60033,
CC         ChEBI:CHEBI:78435; EC=2.4.1.129;
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein.
else
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 51 family.
XX
DR   Pfam; PF00912; Transgly; 1; trigger=no
DR   NCBIfam; TIGR02070; Mono_pep_trsgly; 1; trigger=no
DR   General; Transmembrane; -; 1; trigger=yes
XX
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Cell shape
KW   Cell wall biogenesis/degradation
KW   Glycosyltransferase
KW   Membrane
KW   Peptidoglycan synthesis
KW   Transferase
KW   Transmembrane
KW   Transmembrane helix
XX
GO   GO:0008955; F:peptidoglycan glycosyltransferase activity
GO   GO:0009252; P:peptidoglycan biosynthetic process
GO   GO:0005886; C:plasma membrane
XX
FT   None
XX
Size: 190-300;
Related: None;
Template: P46022; Q48465;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.37 2023/06/01
//