AC   MF_00767;
DC   Protein; auto
TR   HAMAP; MF_00767; -; 1; level=0
XX
Names: Arg_catab_AstE
XX
ID   ASTE
DE   RecName: Full=Succinylglutamate desuccinylase;
DE            EC=3.5.1.96;
GN   Name=astE;
XX
CC   -!- FUNCTION: Transforms N(2)-succinylglutamate into succinate and
CC       glutamate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + N-succinyl-L-glutamate = L-glutamate + succinate;
CC         Xref=Rhea:RHEA:15169, ChEBI:CHEBI:15377, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:30031, ChEBI:CHEBI:58763; EC=3.5.1.96;
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit.;
end case
CC   -!- PATHWAY: Amino-acid degradation; L-arginine degradation via AST
CC       pathway; L-glutamate and succinate from L-arginine: step 5/5.
CC   -!- SIMILARITY: Belongs to the AspA/AstE family. Succinylglutamate
CC       desuccinylase subfamily.
XX
DR   Pfam; PF04952; AstE_AspA; 1; trigger=no
DR   PIRSF; PIRSF017020; AstE; 1; trigger=no
DR   NCBIfam; TIGR03242; Arg_catab_astE; 1; trigger=no
XX
KW   Arginine metabolism
KW   Hydrolase
case <FTGroup:1>
KW   Zinc
KW   Metal-binding
end case
XX
GO   GO:0016788; F:hydrolase activity, acting on ester bonds
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
GO   GO:0019544; P:arginine catabolic process to glutamate
XX
FT   From: ASTE_CHRVO (Q7NU26)
FT   ACT_SITE        214
FT   Condition: E
FT   BINDING         56
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
FT   BINDING         59
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: E
FT   BINDING         149
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
XX
Size: 322-351;
Related: None;
Template: P76215; Q7NU26; Q87Q40;
Scope:
 Bacteria; Pseudomonadota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.26 2023/06/01
//