AC   MF_00786;
DC   Protein; auto
TR   HAMAP; MF_00786; -; 1; level=0
XX
Names: CbiT
XX
ID   CBIT
DE   RecName: Full=Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating);
DE            EC=2.1.1.196;
GN   Name=cbiT;
XX
CC   -!- FUNCTION: Catalyzes the methylation of C-15 in cobalt-precorrin-6B
CC       followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 +
CC         CO2 + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:36067,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:70791, ChEBI:CHEBI:72780; EC=2.1.1.196;
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis;
CC       cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route):
CC       step 8/10.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. Archaeal-type
CC       CbiT family.
XX
DR   Pfam; PF08241; Methyltransf_11; 1; trigger=no
DR   NCBIfam; TIGR02469; CbiT; 1; trigger=no
XX
KW   Cobalamin biosynthesis
KW   Methyltransferase
KW   S-adenosyl-L-methionine
KW   Transferase
XX
GO   GO:0008168; F:methyltransferase activity
GO   GO:0046140; P:corrin biosynthetic process
XX
FT   From: CBIT_METTH (O26249)
FT   BINDING         41..45
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: G-x-[GC]-[TS]-G
FT   BINDING         17
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: T
FT   BINDING         62
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [DE]
FT   BINDING         91
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [AVG]
XX
Size: 163-202;
Related: None;
Template: O26249; Q05632; O87694;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.23 2023/06/01
//