AC   MF_00835;
DC   Protein; auto
TR   HAMAP; MF_00835; -; 1; level=0
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Names: BioC
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ID   BIOC
DE   RecName: Full=Malonyl-[acyl-carrier protein] O-methyltransferase;
DE            Short=Malonyl-ACP O-methyltransferase;
DE            EC=2.1.1.197;
DE   AltName: Full=Biotin synthesis protein BioC;
GN   Name=bioC;
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CC   -!- FUNCTION: Converts the free carboxyl group of a malonyl-thioester to
CC       its methyl ester by transfer of a methyl group from S-adenosyl-L-
CC       methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty
CC       acid synthetic pathway.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=malonyl-[ACP] + S-adenosyl-L-methionine = malonyl-[ACP] methyl
CC         ester + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:17105, Rhea:RHEA-
CC         COMP:9623, Rhea:RHEA-COMP:9954, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:78449, ChEBI:CHEBI:78845; EC=2.1.1.197;
CC   -!- PATHWAY: Cofactor biosynthesis; biotin biosynthesis.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
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DR   PROSITE; PS00599; AA_TRANSFER_CLASS_2; 1; trigger=no
DR   Pfam; PF08241; Methyltransf_11; 1; trigger=no
DR   Pfam; PF08242; Methyltransf_12; 1; trigger=no
DR   NCBIfam; TIGR02072; BioC; 1; trigger=no
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KW   Biotin biosynthesis
KW   Methyltransferase
KW   S-adenosyl-L-methionine
KW   Transferase
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GO   GO:0010340; F:carboxyl-O-methyltransferase activity
GO   GO:0009102; P:biotin biosynthetic process
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Size: 245-350;
Related: None;
Template: P12999; P36571;
Scope:
 Bacteria
Fusion:
 Nter: MF_01260 (BioH)
 Cter: MF_00336 (BioD); <Unknown>
Duplicate: in COXBU, ILYPC
Plasmid: in ILYPC
Comments: None
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# Revision 1.7 2023/06/01
//