AC   MF_00849;
DC   Protein; auto
TR   HAMAP; MF_00849; -; 1; level=0
XX
Names: BipA
XX
ID   BIPA
DE   RecName: Full=Large ribosomal subunit assembly factor BipA;
DE            EC=3.6.5.-;
DE   AltName: Full=GTP-binding protein BipA;
GN   Name=bipA;
XX
CC   -!- FUNCTION: A 50S ribosomal subunit assembly protein with GTPase
CC       activity, required for 50S subunit assembly at low temperatures, may
CC       also play a role in translation. Binds GTP and analogs. Binds the 70S
CC       ribosome between the 30S and 50S subunits, in a similar position as
CC       ribosome-bound EF-G; it contacts a number of ribosomal proteins, both
CC       rRNAs and the A-site tRNA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC   -!- SUBUNIT: Monomer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Note=Binds to ribosomes.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. BipA subfamily.
XX
DR   PROSITE; PS00301; G_TR_1; 1; trigger=no
DR   PROSITE; PS51722; G_TR_2; 1; trigger=yes
DR   Pfam; PF00679; EFG_C; 1; trigger=no
DR   Pfam; PF00009; GTP_EFTU; 1; trigger=no
DR   Pfam; PF03144; GTP_EFTU_D2; 1; trigger=no
DR   PRINTS; PR00315; ELONGATNFCT; 1; trigger=no
DR   NCBIfam; TIGR00231; small_GTP; 1; trigger=no
DR   NCBIfam; TIGR01394; TypA_BipA; 1; trigger=no
XX
KW   Cytoplasm
KW   GTP-binding
KW   Hydrolase
KW   Nucleotide-binding
KW   Ribosome biogenesis
KW   RNA-binding
KW   rRNA-binding
KW   tRNA-binding
XX
GO   GO:0005737; C:cytoplasm
GO   GO:0005525; F:GTP binding
GO   GO:0003924; F:GTPase activity
GO   GO:0043022; F:ribosome binding
GO   GO:0000027; P:ribosomal large subunit assembly
XX
FT   From: BIPA_ECOLI (P0DTT0)
FT   BINDING         15..20
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT   Condition: D-[HA]-G-K-[ST]-[ST]
FT   BINDING         128..131
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT   Condition: N-K-[ITV]-D
XX
Size: 575-643;
Related: None;
Template: P0DTT0; P0A3B2; H9L427;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.6 2023/06/01
//