AC   MF_00901;
DC   Protein; auto
TR   HAMAP; MF_00901; -; 1; level=0
XX
Names: TatD_exonuclease
XX
ID   TATD
DE   RecName: Full=3'-5' ssDNA/RNA exonuclease TatD;
DE            EC=3.1.11.-;
DE            EC=3.1.13.-;
DE   AltName: Full=DNase TatD;
GN   Name=tatD;
XX
CC   -!- FUNCTION: 3'-5' exonuclease that prefers single-stranded DNA and RNA.
CC       May play a role in the H(2)O(2)-induced DNA damage repair.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- SUBUNIT: Monomer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       TatD-type hydrolase family. TatD subfamily.
XX
DR   PROSITE; PS01137; TATD_1; 1; trigger=no
DR   PROSITE; PS01090; TATD_2; 1; trigger=no
DR   PROSITE; PS01091; TATD_3; 1; trigger=no
DR   Pfam; PF01026; TatD_DNase; 1; trigger=no
DR   PIRSF; PIRSF005902; DNase_TatD; 1; trigger=no
XX
KW   Cytoplasm
KW   Exonuclease
KW   Hydrolase
KW   Magnesium
KW   Metal-binding
KW   Nuclease
XX
GO   GO:0008310; F:single-stranded DNA 3'-5' DNA exonuclease activity
GO   GO:0000175; F:3'-5'-RNA exonuclease activity
GO   GO:0000287; F:magnesium ion binding
GO   GO:0090304; P:nucleic acid metabolic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: TATD_ECOLI (P27859)
FT   BINDING         91
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Condition: E
FT   BINDING         127
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Condition: H
FT   BINDING         152
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Condition: H
XX
Size: 255-290;
Related: None;
Template: P27859;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: The family is restricted to Enterobacterales in order to avoid wrong matches.
XX
# Revision 1.12 2023/12/15
//