AC   MF_00934;
DC   Protein; auto
TR   HAMAP; MF_00934; -; 1; level=0
XX
Names: 23SrRNA_methyltr_J
XX
ID   RLMJ
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase J;
DE            EC=2.1.1.266;
DE   AltName: Full=23S rRNA (adenine(2030)-N6)-methyltransferase;
DE   AltName: Full=23S rRNA m6A2030 methyltransferase;
GN   Name=rlmJ;
XX
CC   -!- FUNCTION: Specifically methylates the adenine in position 2030 of 23S
CC       rRNA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) +
CC         N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:43736, Rhea:RHEA-COMP:10668, Rhea:RHEA-COMP:10669,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74411, ChEBI:CHEBI:74449; EC=2.1.1.266;
CC   -!- SUBUNIT: Monomer.
CC   -!- SIMILARITY: Belongs to the RlmJ family.
XX
DR   PROSITE; PS00092; N6_MTASE; 2; trigger=no
DR   Pfam; PF04378; DUF519; 1; trigger=no
XX
KW   Methyltransferase
KW   RNA-binding
KW   rRNA processing
KW   S-adenosyl-L-methionine
KW   Transferase
XX
GO   GO:0036307; F:23S rRNA (adenine(2030)-N(6))-methyltransferase activity
GO   GO:0003723; F:RNA binding
GO   GO:0070475; P:rRNA base methylation
XX
FT   From: RLMJ_ECOLI (P37634)
FT   BINDING         143..144
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: [DNE]-[GAS]
FT   ACT_SITE        164
FT                   /note="Proton acceptor"
FT   Condition: D
FT   BINDING         19
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: H
FT   BINDING         42
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [HYFN]
FT   BINDING         100
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: S
FT   BINDING         118
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [ED]
FT   BINDING         164
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: D
FT   SITE            4
FT                   /note="Interaction with substrate rRNA"
FT   Condition: Y
XX
Size: 240-362;
Related: None;
Template: P37634;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.9 2022/11/19
//