AC   MF_00951;
DC   Protein; auto
TR   HAMAP; MF_00951; -; 1; level=0
XX
Names: RfaH
XX
ID   RFAH
DE   RecName: Full=Transcription antitermination protein RfaH;
GN   Name=rfaH;
XX
case <OC:Enterobacterales>
CC   -!- FUNCTION: Enhances distal genes transcription elongation in a
CC       specialized subset of operons that encode extracytoplasmic components.
CC       RfaH is recruited into a multi-component RNA polymerase complex by the
CC       ops element, which is a short conserved DNA sequence located downstream
CC       of the main promoter of these operons. Once bound, RfaH suppresses
CC       pausing and inhibits Rho-dependent and intrinsic termination at a
CC       subset of sites. Termination signals are bypassed, which allows
CC       complete synthesis of long RNA chains.
else
CC   -!- FUNCTION: Enhances distal genes transcription elongation in a
CC       specialized subset of operons that encode extracytoplasmic components.
end case
CC   -!- SUBUNIT: Interacts with both the nontemplate DNA and the RNA polymerase
CC       (RNAP).
CC   -!- SIMILARITY: Belongs to the RfaH family.
XX
DR   Pfam; PF02357; NusG; 1; trigger=no
DR   NCBIfam; TIGR01955; RfaH; 1; trigger=no
XX
KW   DNA-binding
KW   Transcription
KW   Transcription antitermination
KW   Transcription regulation
XX
GO   GO:0003677; F:DNA binding
GO   GO:0001073; F:transcription antitermination factor activity, DNA binding
GO   GO:0031564; P:transcription antitermination
XX
FT   None
XX
Size: 150-224;
Related: None;
Template: P0AFW0;
Scope:
 Bacteria; Pseudomonadota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.7 2023/06/01
//