AC   MF_00965;
DC   Protein; auto
TR   HAMAP; MF_00965; -; 1; level=0
XX
Names: DEAD_helicase_DbpA
XX
ID   DBPA
DE   RecName: Full=ATP-dependent RNA helicase DbpA;
DE            EC=3.6.4.13;
GN   Name=dbpA;
XX
CC   -!- FUNCTION: DEAD-box RNA helicase involved in the assembly of the 50S
CC       ribosomal subunit. Has an RNA-dependent ATPase activity, which is
CC       specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses
CC       the energy of ATP hydrolysis to destabilize and unwind short rRNA
CC       duplexes.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- DOMAIN: Contains an N-terminal domain that binds non-specifically to
CC       RNA and a C-terminal domain that binds specifically and tightly to
CC       hairpin 92 of 23S rRNA.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DbpA subfamily.
XX
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1; trigger=no
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1; trigger=yes
DR   PROSITE; PS51194; HELICASE_CTER; 1; trigger=yes
DR   PROSITE; PS51195; Q_MOTIF; 1; trigger=yes
DR   Pfam; PF03880; DbpA; 1; trigger=no
DR   Pfam; PF00270; DEAD; 1; trigger=no
DR   Pfam; PF00271; Helicase_C; 1; trigger=no
XX
KW   ATP-binding
KW   Cytoplasm
KW   Helicase
KW   Hydrolase
KW   Nucleotide-binding
KW   Ribosome biogenesis
KW   RNA-binding
XX
GO   GO:0005524; F:ATP binding
GO   GO:0034458; F:3'-5' RNA helicase activity
GO   GO:0003723; F:RNA binding
GO   GO:0000027; P:ribosomal large subunit assembly
GO   GO:0005737; C:cytoplasm
XX
FT   From: DBPA_BACSU (P42305)
FT   REGION          404..Cter
FT                   /note="Involved in 23S rRNA binding"
XX
Size: 430-529;
Related: None;
Template: P42305; P21693;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2019/11/19
//