AC   MF_00983;
DC   Protein; auto
TR   HAMAP; MF_00983; -; 1; level=0
XX
Names: PriA
XX
ID   PRIA
case not <Feature:PS51192> and not <Feature:PS51194>
DE   RecName: Full=Probable primosomal protein N';
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase PriA;
else
DE   RecName: Full=Primosomal protein N';
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase PriA;
end case
GN   Name=priA;
XX
CC   -!- FUNCTION: Involved in the restart of stalled replication forks.
CC       Recognizes and binds the arrested nascent DNA chain at stalled
CC       replication forks. It can open the DNA duplex, via its helicase
CC       activity, and promote assembly of the primosome and loading of the
CC       major replicative helicase DnaB onto DNA.
CC   -!- SUBUNIT: Component of the primosome.
CC   -!- SIMILARITY: Belongs to the helicase family. PriA subfamily.
XX
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 0-1; trigger=yes
DR   PROSITE; PS51194; HELICASE_CTER; 0-1; trigger=yes
DR   Pfam; PF00270; DEAD; 1; trigger=no
DR   Pfam; PF00271; Helicase_C; 1; trigger=no
DR   NCBIfam; TIGR00595; priA; 1; trigger=no
XX
KW   ATP-binding
KW   DNA replication
KW   DNA-binding
KW   Helicase
KW   Hydrolase
KW   Nucleotide-binding
KW   Primosome
case <FTTag:zinc>
KW   Metal-binding
KW   Zinc
KW   Zinc-finger
end case
XX
GO   GO:0003678; F:DNA helicase activity
GO   GO:0005524; F:ATP binding
GO   GO:0003677; F:DNA binding
case <FTTag:zinc>
GO   GO:0008270; F:zinc ion binding
end case
GO   GO:0006268; P:DNA unwinding involved in DNA replication
GO   GO:1990077; C:primosome complex
XX
FT   From: PRIA_ECOLI (P17888)
FT   ZN_FING         436..448
FT                   /note="C4-type"
FT   Tag: zinc; Condition: C-x(2)-C-x(5)-C-x(2)-C
FT   ZN_FING         463..479
FT                   /note="C4-type"
FT   Tag: zinc; Condition: C-x(2)-C-x(7,10)-C-x(2)-C
XX
Size: 535-950;
Related: None;
Template: P17888;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2023/06/01
//