AC   MF_00994;
DC   Protein; auto
TR   HAMAP; MF_00994; -; 1; level=0
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Names: LPS_assembly_LapB
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ID   LAPB
DE   RecName: Full=Lipopolysaccharide assembly protein B;
GN   Name=lapB;
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CC   -!- FUNCTION: Modulates cellular lipopolysaccharide (LPS) levels by
CC       regulating LpxC, which is involved in lipid A biosynthesis. May act by
CC       modulating the proteolytic activity of FtsH towards LpxC. May also
CC       coordinate assembly of proteins involved in LPS synthesis at the plasma
CC       membrane.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein; Cytoplasmic side.
CC   -!- SIMILARITY: Belongs to the LapB family.
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DR   PROSITE; PS50005; TPR; 1; trigger=no
DR   PROSITE; PS50293; TPR_REGION; 1; trigger=no
DR   Pfam; PF07719; TPR_2; 1; trigger=no
DR   Pfam; PF13176; TPR_7; 1; trigger=no
DR   Pfam; PF00515; TPR_1; 1; trigger=no
DR   REP; Repeat_TPR; TPR; 2-7; trigger=yes
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KW   Cell inner membrane
KW   Cell membrane
KW   Membrane
KW   Repeat
KW   TPR repeat
KW   Transmembrane
KW   Transmembrane helix
case <FTGroup:1>
KW   Iron
KW   Metal-binding
end case
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case <FTGroup:1>
GO   GO:0005506; F:iron ion binding
end case
GO   GO:0046890; P:regulation of lipid biosynthetic process
GO   GO:0009898; C:cytoplasmic side of plasma membrane
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FT   From: LAPB_ECOLI (P0AB58)
FT   TRANSMEM        1..20
FT                   /note="Helical"
FT   TOPO_DOM        21..Cter
FT                   /note="Cytoplasmic"
FT   BINDING         357
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Group: 1; Condition: C
FT   BINDING         360
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Group: 1; Condition: C
FT   BINDING         371
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Group: 1; Condition: C
FT   BINDING         374
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Group: 1; Condition: C
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Size: 350-430;
Related: None;
Template: P0AB58;
Scope:
 Bacteria; Pseudomonadota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.8 2023/01/26
//