AC   MF_01002;
DC   Protein; auto
TR   HAMAP; MF_01002; -; 1; level=0
XX
Names: WecF_RffT
XX
ID   WECF
DE   RecName: Full=TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase;
DE            EC=2.4.1.325;
DE   AltName: Full=4-alpha-L-fucosyltransferase;
DE   AltName: Full=TDP-Fuc4NAc:lipid II Fuc4NAc transferase;
DE            Short=Fuc4NAc transferase;
GN   Name=wecF; Synonyms=rffT;
XX
CC   -!- FUNCTION: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc
CC       (Lipid III), the third lipid-linked intermediate involved in ECA
CC       synthesis.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-
CC         undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-
CC         galactose = alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-
CC         undecaprenyl diphosphate + dTDP + H(+); Xref=Rhea:RHEA:28759,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:58369, ChEBI:CHEBI:61495,
CC         ChEBI:CHEBI:61496, ChEBI:CHEBI:68493; EC=2.4.1.325;
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial common
CC       antigen biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 56 family.
XX
DR   Pfam; PF07429; Glyco_transf_56; 1; trigger=no
XX
KW   Transferase
KW   Glycosyltransferase
KW   Membrane
KW   Cell membrane
KW   Cell inner membrane
XX
GO   GO:0016758; F:hexosyltransferase activity
GO   GO:0009246; P:enterobacterial common antigen biosynthetic process
GO   GO:0005886; C:plasma membrane
XX
FT   None
XX
Size: 359-361;
Related: None;
Template: P56258;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.31 2021/06/03
//