AC   MF_01005;
DC   Protein; auto
TR   HAMAP; MF_01005; -; 1; level=0
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Names: BtuD
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ID   BTUD
DE   RecName: Full=Vitamin B12 import ATP-binding protein BtuD;
DE            EC=7.6.2.8;
DE   AltName: Full=Vitamin B12-transporting ATPase;
GN   Name=btuD;
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CC   -!- FUNCTION: Part of the ABC transporter complex BtuCDF involved in
CC       vitamin B12 import. Responsible for energy coupling to the transport
CC       system.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an R-cob(III)alamin(out) + ATP + H2O = ADP + an R-
CC         cob(III)alamin(in) + H(+) + phosphate; Xref=Rhea:RHEA:17873,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:140785, ChEBI:CHEBI:456216;
CC         EC=7.6.2.8;
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (BtuD),
CC       two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Vitamin B12
CC       importer (TC 3.A.1.13.1) family.
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DR   Pfam; PF00005; ABC_tran; 1; trigger=no
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1; trigger=no
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1; trigger=yes
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KW   ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Membrane
KW   Nucleotide-binding
KW   Translocase
KW   Transport
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GO   GO:0015420; F:ABC-type vitamin B12 transporter activity
GO   GO:0015889; P:cobalamin transport
GO   GO:0005886; C:plasma membrane
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FT   From: BTUD_ECOLI (P06611)
FT   BINDING         33..40
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: G-P-N-G-[ASC]-G-K-S
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Size: 249-255;
Related: None;
Template: P06611;
Scope:
 Bacteria; Enterobacterales
 Bacteria; Vibrionaceae
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.41 2022/11/19
//