AC   MF_01009;
DC   Protein; auto
TR   HAMAP; MF_01009; -; 1; level=0
XX
Names: Thiosulf_sulfurtr
XX
ID   GLPE
DE   RecName: Full=Thiosulfate sulfurtransferase GlpE;
DE            EC=2.8.1.1;
GN   Name=glpE;
XX
CC   -!- FUNCTION: Transferase that catalyzes the transfer of sulfur from
CC       thiosulfate to thiophilic acceptors such as cyanide or dithiols. May
CC       function in a CysM-independent thiosulfate assimilation pathway by
CC       catalyzing the conversion of thiosulfate to sulfite, which can then be
CC       used for L-cysteine biosynthesis.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2
CC         H(+); Xref=Rhea:RHEA:16881, ChEBI:CHEBI:15378, ChEBI:CHEBI:17359,
CC         ChEBI:CHEBI:18022, ChEBI:CHEBI:18407, ChEBI:CHEBI:33542; EC=2.8.1.1;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=thiosulfate + [thioredoxin]-dithiol = [thioredoxin]-disulfide
CC         + hydrogen sulfide + sulfite + 2 H(+); Xref=Rhea:RHEA:83859,
CC         Rhea:RHEA-COMP:10698, Rhea:RHEA-COMP:10700, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:17359, ChEBI:CHEBI:29919, ChEBI:CHEBI:29950,
CC         ChEBI:CHEBI:33542, ChEBI:CHEBI:50058;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the GlpE family.
XX
DR   Pfam; PF00581; Rhodanese; 1; trigger=no
DR   PROSITE; PS50206; RHODANESE_3; 1; trigger=yes
XX
KW   Cytoplasm
KW   Transferase
XX
GO   GO:0004792; F:thiosulfate-cyanide sulfurtransferase activity
GO   GO:0005737; C:cytoplasm
XX
FT   From: GLPE_ECOLI (P0A6V5)
FT   ACT_SITE        65
FT                   /note="Cysteine persulfide intermediate"
FT   Condition: C
XX
Size: 95-140;
Related: None;
Template: P0A6V5;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Version: 22
# Last updated date: 2025-03-21
# Created date: 2005-02-28
//