AC   MF_01017;
DC   Protein; auto
TR   HAMAP; MF_01017; -; 1; level=0
XX
Names: NQOR
XX
ID   NQOR
DE   RecName: Full=NAD(P)H dehydrogenase (quinone);
DE            EC=1.6.5.2;
DE   AltName: Full=NAD(P)H:quinone oxidoreductase;
DE            Short=NQO;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + H(+) + NADH = a quinol + NAD(+);
CC         Xref=Rhea:RHEA:46160, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124; EC=1.6.5.2;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + H(+) + NADPH = a quinol + NADP(+);
CC         Xref=Rhea:RHEA:46164, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:132124; EC=1.6.5.2;
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC       Note=Binds 1 FMN per monomer.;
CC   -!- SIMILARITY: Belongs to the WrbA family.
XX
DR   Pfam; PF00258; Flavodoxin_1; 1; trigger=no
DR   NCBIfam; TIGR01755; Flav_wrbA; 1; trigger=no
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1; trigger=no
XX
KW   Flavoprotein
KW   FMN
KW   NAD
KW   NADP
KW   Nucleotide-binding
KW   Oxidoreductase
XX
GO   GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity
GO   GO:0050660; F:flavin adenine dinucleotide binding
GO   GO:0050661; F:NADP binding
GO   GO:0051287; F:NAD binding
XX
FT   From: NQOR_ECOLI (P0A8G6)
FT   DOMAIN          4..189
FT                   /note="Flavodoxin-like"
FT   BINDING         10..15
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT   Condition: S-x-[YWH]-[GA]-[HY]-[ILVMT]
FT   BINDING         78..80
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT   Condition: [TA]-R-[FY]
FT   BINDING         113..118
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT   Condition: S-[TS]-[GA]-[TS]-x(1,2)-G
FT   BINDING         12
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT   Condition: [YW]
FT   BINDING         98
FT                   /ligand="substrate"
FT   Condition: W
FT   BINDING         133
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT   Condition: H
XX
Size: 188-230;
Related: None;
Template: P0A8G6; A1A9Q9; C1I202;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in RHIME
Plasmid: in PARDP, CUPMC, RHIME
Comments: None
XX
# Revision 1.37 2023/06/01
//