AC   MF_01031;
DC   Protein; auto
TR   HAMAP; MF_01031; -; 1; level=0
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Names: LeuD_type1
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ID   LEUD
DE   RecName: Full=3-isopropylmalate dehydratase small subunit;
DE            EC=4.2.1.33;
DE   AltName: Full=Alpha-IPM isomerase;
DE            Short=IPMI;
DE   AltName: Full=Isopropylmalate isomerase;
GN   Name=leuD;
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CC   -!- FUNCTION: Catalyzes the isomerization between 2-isopropylmalate and 3-
CC       isopropylmalate, via the formation of 2-isopropylmaleate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate;
CC         Xref=Rhea:RHEA:32287, ChEBI:CHEBI:1178, ChEBI:CHEBI:35121;
CC         EC=4.2.1.33;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine
CC       from 3-methyl-2-oxobutanoate: step 2/4.
CC   -!- SUBUNIT: Heterodimer of LeuC and LeuD.
CC   -!- SIMILARITY: Belongs to the LeuD family. LeuD type 1 subfamily.
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DR   Pfam; PF00694; Aconitase_C; 1; trigger=no
DR   NCBIfam; TIGR00171; LeuD; 1; trigger=no
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KW   Amino-acid biosynthesis
KW   Branched-chain amino acid biosynthesis
KW   Leucine biosynthesis
KW   Lyase
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GO   GO:0003861; F:3-isopropylmalate dehydratase activity
GO   GO:0009098; P:leucine biosynthetic process
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FT   None
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Size: 189-230;
Related: MF_01032;
Template: P04787;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in BORBR, BORPA, BORPE, CHRVO, MANSM, SALCH, SALTY
Plasmid: in BUCAI, BUCAP, BUCDN, BUCPP, BUCRP, BUCTS
Comments: None
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# Revision 1.30 2023/06/01
//