AC MF_01043; DC Protein; auto TR HAMAP; MF_01043; -; 1; level=0 XX Names: PlsY XX ID PLSY case or or DE RecName: Full=Glycerol-3-phosphate acyltransferase; DE AltName: Full=G3P acyltransferase; DE Short=GPAT; DE EC=2.3.1.15; DE EC=2.3.1.n5; DE AltName: Full=Lysophosphatidic acid synthase; DE Short=LPA synthase; else DE RecName: Full=Glycerol-3-phosphate acyltransferase; DE AltName: Full=Acyl-PO4 G3P acyltransferase; DE AltName: Full=Acyl-phosphate--glycerol-3-phosphate acyltransferase; DE AltName: Full=G3P acyltransferase; DE Short=GPAT; DE EC=2.3.1.275; DE AltName: Full=Lysophosphatidic acid synthase; DE Short=LPA synthase; end case GN Name=plsY; XX case or or CC -!- FUNCTION: Catalyzes the transfer of an acyl group from acyl-ACP to CC glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This CC enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl- CC PO(4). CC -!- CATALYTIC ACTIVITY: CC Reaction=an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3- CC phosphate + CoA; Xref=Rhea:RHEA:15325, ChEBI:CHEBI:57287, CC ChEBI:CHEBI:57597, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342; EC=2.3.1.15; CC -!- CATALYTIC ACTIVITY: CC Reaction=a fatty acyl-[ACP] + sn-glycerol 3-phosphate = a 1-acyl-sn- CC glycero-3-phosphate + holo-[ACP]; Xref=Rhea:RHEA:42300, Rhea:RHEA- CC COMP:9685, Rhea:RHEA-COMP:14125, ChEBI:CHEBI:57597, CC ChEBI:CHEBI:57970, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651; CC EC=2.3.1.n5; else CC -!- FUNCTION: Catalyzes the transfer of an acyl group from acyl-phosphate CC (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic CC acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, CC but not acyl-CoA or acyl-ACP. CC -!- CATALYTIC ACTIVITY: CC Reaction=an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn- CC glycero-3-phosphate + phosphate; Xref=Rhea:RHEA:34075, CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57597, ChEBI:CHEBI:57970, CC ChEBI:CHEBI:59918; EC=2.3.1.275; end case CC -!- PATHWAY: Lipid metabolism; phospholipid metabolism. CC -!- SUBUNIT: Probably interacts with PlsX. case not defined or CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. else case CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein. end case CC -!- SIMILARITY: Belongs to the PlsY family. XX DR Pfam; PF02660; G3P_acyltransf; 1; trigger=no DR NCBIfam; TIGR00023; TIGR00023; 1; trigger=no case not and not and not DR General; Transmembrane; -; 4-6; trigger=yes end case XX case defined and KW Cell inner membrane end case KW Cell membrane KW Lipid biosynthesis KW Lipid metabolism KW Membrane KW Phospholipid biosynthesis KW Phospholipid metabolism KW Transferase KW Transmembrane KW Transmembrane helix XX case or or GO GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity end case case not and not and not GO GO:0043772; F:acyl-phosphate glycerol-3-phosphate acyltransferase activity end case GO GO:0008654; P:phospholipid biosynthetic process XX FT From: PLSY_ECOLI (P60782) case or or FT TOPO_DOM 1..3 FT /note="Periplasmic" FT TRANSMEM 4..24 FT /note="Helical" FT TOPO_DOM 25..52 FT /note="Cytoplasmic" FT TRANSMEM 53..73 FT /note="Helical" FT TOPO_DOM 74..80 FT /note="Periplasmic" FT TRANSMEM 81..101 FT /note="Helical" FT TOPO_DOM 102..111 FT /note="Cytoplasmic" FT TRANSMEM 112..132 FT /note="Helical" FT TOPO_DOM 133..137 FT /note="Periplasmic" FT TRANSMEM 138..158 FT /note="Helical" FT TOPO_DOM 159..205 FT /note="Cytoplasmic" end case XX Size: 172-327; Related: None; Template: P60782; Q45064; P0A4Q0; Scope: Bacteria Fusion: Nter: None Cter: None Duplicate: in BACAN, BACC1, BACCR, BACCZ, BACHK, DEHM1, DEHMC, DEIRA, DESHY, LACAC, LACJO, MOOTA, OCEIH, RHIJ3, THEMA Plasmid: None Comments: None XX # Revision 1.51 2023/11/28 //