AC   MF_01049;
DC   Protein; auto
TR   HAMAP; MF_01049; -; 1; level=0
XX
Names: CaiT
XX
ID   CAIT
DE   RecName: Full=L-carnitine/gamma-butyrobetaine antiporter;
GN   Name=caiT;
XX
CC   -!- FUNCTION: Catalyzes the exchange of L-carnitine for gamma-
CC       butyrobetaine.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-carnitine(out) + 4-(trimethylamino)butanoate(in) = (R)-
CC         carnitine(in) + 4-(trimethylamino)butanoate(out);
CC         Xref=Rhea:RHEA:29427, ChEBI:CHEBI:16244, ChEBI:CHEBI:16347;
CC   -!- PATHWAY: Amine and polyamine metabolism; carnitine metabolism.
CC   -!- SUBUNIT: Homotrimer.
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family. CaiT
CC       subfamily.
XX
DR   Pfam; PF02028; BCCT; 1; trigger=no
DR   NCBIfam; TIGR00842; bcct; 1; trigger=no
DR   PROSITE; PS01303; BCCT; 1; trigger=no
DR   General; Transmembrane; -; 12; trigger=yes
XX
KW   Transport
KW   Antiport
KW   Membrane
KW   Transmembrane
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Transmembrane helix
XX
GO   GO:0044667; F:(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity
GO   GO:1902603; P:carnitine transmembrane transport
GO   GO:0005886; C:plasma membrane
XX
FT   None
XX
Size: 504-505;
Related: None;
Template: P31553; B4EY22;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.34 2023/06/01
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