AC   MF_01050;
DC   Protein; auto
TR   HAMAP; MF_01050; -; 1; level=0
XX
Names: CaiB
XX
ID   CAIB
DE   RecName: Full=L-carnitine CoA-transferase;
DE            EC=2.8.3.21;
DE   AltName: Full=Crotonobetainyl-CoA:carnitine CoA-transferase;
GN   Name=caiB;
XX
CC   -!- FUNCTION: Catalyzes the reversible transfer of the CoA moiety from
CC       gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA
CC       and gamma-butyrobetaine. Is also able to catalyze the reversible
CC       transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-
CC       carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-carnitine + crotonobetainyl-CoA = (R)-carnitinyl-CoA +
CC         crotonobetaine; Xref=Rhea:RHEA:28526, ChEBI:CHEBI:16347,
CC         ChEBI:CHEBI:17237, ChEBI:CHEBI:60932, ChEBI:CHEBI:60933; EC=2.8.3.21;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-carnitine + 4-(trimethylamino)butanoyl-CoA = (R)-
CC         carnitinyl-CoA + 4-(trimethylamino)butanoate; Xref=Rhea:RHEA:28418,
CC         ChEBI:CHEBI:16244, ChEBI:CHEBI:16347, ChEBI:CHEBI:60932,
CC         ChEBI:CHEBI:61513; EC=2.8.3.21;
CC   -!- PATHWAY: Amine and polyamine metabolism; carnitine metabolism.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the CoA-transferase III family. CaiB subfamily.
XX
DR   Pfam; PF02515; CoA_transf_3; 1; trigger=no
XX
KW   Cytoplasm
KW   Transferase
XX
GO   GO:0008410; F:CoA-transferase activity
GO   GO:0005737; C:cytoplasm
XX
FT   From: CAIB_ECOLI (P31572)
FT   ACT_SITE        169
FT                   /note="Nucleophile"
FT   Condition: D
FT   BINDING         97
FT                   /ligand="CoA"
FT                   /ligand_id="ChEBI:CHEBI:57287"
FT   Condition: K
FT   BINDING         104
FT                   /ligand="CoA"
FT                   /ligand_id="ChEBI:CHEBI:57287"
FT   Condition: R
XX
Size: 405-406;
Related: None;
Template: P31572; Q8GB19;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.24 2022/12/15
//