AC   MF_01062;
DC   Protein; auto
TR   HAMAP; MF_01062; -; 1; level=0
XX
Names: PSRP
XX
ID   PSRP
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
DE   RecName: Full=Phosphoenolpyruvate synthase regulatory protein;
DE            Short=PEP synthase regulatory protein;
DE            Short=PSRP;
DE            EC=2.7.11.33;
DE            EC=2.7.4.28;
DE   AltName: Full=Pyruvate, water dikinase regulatory protein;
GN   Name=ppsR;
else
DE   RecName: Full=Putative phosphoenolpyruvate synthase regulatory protein;
DE            Short=PEP synthase regulatory protein;
DE            Short=PSRP;
DE            EC=2.7.11.33;
DE            EC=2.7.4.28;
DE   AltName: Full=Pyruvate, water dikinase regulatory protein;
end case
XX
CC   -!- FUNCTION: Bifunctional serine/threonine kinase and phosphorylase
CC       involved in the regulation of the phosphoenolpyruvate synthase (PEPS)
CC       by catalyzing its phosphorylation/dephosphorylation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]-
CC         phosphate + AMP + H(+); Xref=Rhea:RHEA:46020, Rhea:RHEA-COMP:11425,
CC         Rhea:RHEA-COMP:11426, ChEBI:CHEBI:15378, ChEBI:CHEBI:43176,
CC         ChEBI:CHEBI:68546, ChEBI:CHEBI:456215, ChEBI:CHEBI:456216;
CC         EC=2.7.11.33;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[pyruvate, water dikinase]-phosphate + H(+) + phosphate =
CC         [pyruvate, water dikinase] + diphosphate; Xref=Rhea:RHEA:48580,
CC         Rhea:RHEA-COMP:11425, Rhea:RHEA-COMP:11426, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:43176, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:68546; EC=2.7.4.28;
CC   -!- SIMILARITY: Belongs to the pyruvate, phosphate/water dikinase
CC       regulatory protein family. PSRP subfamily.
XX
DR   Pfam; PF03618; Kinase-PPPase; 1; trigger=no
XX
KW   Kinase
KW   Serine/threonine-protein kinase
KW   Transferase
KW   Nucleotide-binding
XX
GO   GO:0004674; F:protein serine/threonine kinase activity
GO   GO:0016776; F:phosphotransferase activity, phosphate group as acceptor
GO   GO:0043531; F:ADP binding
GO   GO:0006468; P:protein phosphorylation
GO   GO:0006470; P:protein dephosphorylation
XX
FT   From: PSRP_ECOLI (P0A8A4)
FT   BINDING         157..164
FT                   /ligand="ADP"
FT                   /ligand_id="ChEBI:CHEBI:456216"
FT   Condition: [GA]-x-S-R-x-[GS]-K-[TS]
XX
Size: 258-315;
Related: None;
Template: P0A8A4;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.34 2022/11/19
//