AC MF_01105; DC Protein; auto TR HAMAP; MF_01105; -; 1; level=0 XX Names: N_acetyl_glu_synth XX ID ARGA DE RecName: Full=Amino-acid acetyltransferase; DE EC=2.3.1.1; DE AltName: Full=N-acetylglutamate synthase; DE Short=AGS; DE Short=NAGS; GN Name=argA; XX CC -!- CATALYTIC ACTIVITY: CC Reaction=acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate; CC Xref=Rhea:RHEA:24292, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, CC ChEBI:CHEBI:44337, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.1; CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl- CC L-ornithine from L-glutamate: step 1/4. case CC -!- SUBUNIT: Homohexamer. end case CC -!- SUBCELLULAR LOCATION: Cytoplasm. case not and not and not CC -!- MISCELLANEOUS: In bacteria which possess the bifunctional enzyme CC ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA CC fulfills an anaplerotic role. end case CC -!- SIMILARITY: Belongs to the acetyltransferase family. ArgA subfamily. XX DR Pfam; PF00696; AA_kinase; 1; trigger=no DR Pfam; PF00583; Acetyltransf_1; 1; trigger=no DR PIRSF; PIRSF000423; ArgA; 1; trigger=no DR NCBIfam; TIGR01890; N-Ac-Glu-synth; 1; trigger=no DR PROSITE; PS51186; GNAT; 1; trigger=yes XX KW Cytoplasm KW Amino-acid biosynthesis KW Arginine biosynthesis KW Transferase KW Acyltransferase XX GO GO:0004042; F:acetyl-CoA:L-glutamate N-acetyltransferase activity GO GO:0006526; P:arginine biosynthetic process GO GO:0005737; C:cytoplasm XX FT None XX Size: 432-451; Related: None; Template: P0A6C5; Scope: Bacteria; Pseudomonadota Fusion: Nter: MF_00006 (argH) Cter: None Duplicate: None Plasmid: None Comments: Moritella sp. argA is fusioned in its N-terminal part to argH. The NAT domain is not shown here - it is much smaller than other acetylglutamate synthases. XX # Revision 1.36 2023/06/01 //