AC   MF_01116;
DC   Protein; auto
c?   <OC:Archaea>
TR   HAMAP; MF_01116; -; 1; level=0
XX
Names: TSR3
XX
ID   TSR3
DE   RecName: Full=16S rRNA aminocarboxypropyltransferase;
DE            EC=2.5.1.157;
XX
CC   -!- FUNCTION: Aminocarboxypropyltransferase that catalyzes the
CC       aminocarboxypropyl transfer on pseudouridine corresponding to position
CC       914 in M.jannaschii 16S rRNA. It constitutes the last step in
CC       biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-
CC       carboxypropyl) pseudouridine (m1acp3-Psi).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine
CC         = H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine
CC         in rRNA + S-methyl-5'-thioadenosine; Xref=Rhea:RHEA:63296, Rhea:RHEA-
CC         COMP:11634, Rhea:RHEA-COMP:16310, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:17509, ChEBI:CHEBI:59789, ChEBI:CHEBI:74890,
CC         ChEBI:CHEBI:146234; EC=2.5.1.157;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the TDD superfamily. TSR3 family.
XX
DR   Pfam; PF04034; Ribo_biogen_C; 1; trigger=no
DR   Pfam; PF04068; RLI; 1; trigger=no
XX
KW   Cytoplasm
KW   Ribosome biogenesis
KW   rRNA processing
KW   S-adenosyl-L-methionine
KW   Transferase
XX
GO   GO:0005737; C:cytoplasm
GO   GO:1904047; F:S-adenosyl-L-methionine binding
GO   GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis
GO   GO:0006364; P:rRNA processing
XX
FT   From: TSR3_VULDI (E1QU22)
FT   BINDING         19
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: [TS]
FT   BINDING         69
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: [IVL]
FT   BINDING         93
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: [LI]
FT   BINDING         108
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: [YW]
FT   BINDING         112
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: [TS]
XX
Size: 163-208;
Related: None;
Template: Q12094; E1QU22;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.27 2024/02/15
//