AC MF_01117; DC Protein; auto TR HAMAP; MF_01117; -; 1; level=0 XX Names: CDP_archaeol_synth XX ID CDPAS DE RecName: Full=CDP-archaeol synthase; DE EC=2.7.7.67; DE AltName: Full=CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase; GN Name=carS; XX CC -!- FUNCTION: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- CC glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- CC phosphate (DGGGP) and CTP. This reaction is the third ether-bond- CC formation step in the biosynthesis of archaeal membrane lipids. CC -!- CATALYTIC ACTIVITY: CC Reaction=2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + CTP + CC H(+) = CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + diphosphate; CC Xref=Rhea:RHEA:25690, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, CC ChEBI:CHEBI:37563, ChEBI:CHEBI:58837, ChEBI:CHEBI:58838; EC=2.7.7.67; CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; CC -!- PATHWAY: Membrane lipid metabolism; glycerophospholipid metabolism. CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. CC -!- SIMILARITY: Belongs to the CDP-archaeol synthase family. XX DR Pfam; PF01864; DUF46; 1; trigger=no DR General; Transmembrane; -; 2-5; trigger=yes XX KW Cell membrane KW Lipid biosynthesis KW Lipid metabolism KW Magnesium KW Membrane KW Phospholipid biosynthesis KW Phospholipid metabolism KW Transferase KW Transmembrane KW Transmembrane helix XX GO GO:0016779; F:nucleotidyltransferase activity GO GO:0046474; P:glycerophospholipid biosynthetic process GO GO:0005886; C:plasma membrane XX FT None XX Size: 149-240; Related: None; Template: O28534; Scope: Archaea Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: None XX # Revision 1.31 2022/09/29 //