AC   MF_01134;
DC   Protein; auto
TR   HAMAP; MF_01134; -; 1; level=0
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Names: CdhB
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ID   ACDE
DE   RecName: Full=Acetyl-CoA decarbonylase/synthase complex subunit epsilon;
DE            Short=ACDS complex subunit epsilon;
DE   AltName: Full=ACDS complex carbon monoxide dehydrogenase subunit epsilon;
DE            Short=ACDS CODH subunit epsilon;
GN   Name=cdhB;
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case <OC:Methanosarcinaceae>
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible cleavage of
CC       acetyl-CoA, allowing growth on acetate as sole source of carbon and
CC       energy. The alpha-epsilon subcomponent functions as a carbon monoxide
CC       dehydrogenase. The precise role of the epsilon subunit is unclear; it
CC       may have a stabilizing role within the alpha(2)epsilon(2) component
CC       and/or be involved in electron transfer to FAD during a potential FAD-
CC       mediated CO oxidation.
end case
case not <OC:Methanosarcinaceae>
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible cleavage of
CC       acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon
CC       subcomponent functions as a carbon monoxide dehydrogenase. The precise
CC       role of the epsilon subunit is unclear; it may have a stabilizing role
CC       within the alpha(2)epsilon(2) component and/or be involved in electron
CC       transfer to FAD during a potential FAD-mediated CO oxidation.
end case
case <OC:Methanosarcinaceae>
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from acetate.
end case
CC   -!- SUBUNIT: Heterotetramer of two alpha and two epsilon subunits. The ACDS
CC       complex is made up of alpha, epsilon, beta, gamma and delta subunits
CC       with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-
CC       (gamma(1)delta(1))(8).
CC   -!- SIMILARITY: Belongs to the CdhB family.
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DR   Pfam; PF02552; CO_dh; 1; trigger=no
DR   NCBIfam; TIGR00315; CdhB; 1; trigger=no
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case <OC:Methanosarcinaceae>
KW   Methanogenesis
end case
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case <OC:Methanosarcinaceae>
GO   GO:0019385; P:methanogenesis, from acetate
end case
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FT   None
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Size: 146-187;
Related: None;
Template: Q9C4Z3; Q46G05;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in ARCFU, METAC, METMA, METTE
Plasmid: None
Comments: None
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# Revision 1.14 2023/06/01
//