AC MF_01141; DC Protein; auto TR HAMAP; MF_01141; -; 1; level=0 XX Names: LrgA XX ID LRGA DE RecName: Full=Antiholin-like protein LrgA; GN Name=lrgA; XX case CC -!- FUNCTION: Inhibits the expression or activity of extracellular murein CC hydrolases by interacting, possibly with LrgB, with the holin-like CC proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the CC proton motive force of the membrane. May be involved in programmed cell CC death (PCD), possibly triggering PCD in response to antibiotics and CC environmental stresses. else CC -!- FUNCTION: Inhibits the expression or activity of extracellular murein CC hydrolases by interacting, possibly with LrgB, with the holin-like CC protein CidA. The LrgAB and CidA proteins may affect the proton motive CC force of the membrane. May be involved in programmed cell death (PCD), CC possibly triggering PCD in response to antibiotics and environmental CC stresses. end case CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. CC -!- SIMILARITY: Belongs to the CidA/LrgA family. LrgA subfamily. XX DR Pfam; PF03788; LrgA; 1; trigger=no DR General; Transmembrane; -; 4; trigger=yes XX KW Cell membrane KW Cytolysis KW Membrane KW Transmembrane KW Transmembrane helix XX GO GO:0019835; P:cytolysis GO GO:0012501; P:programmed cell death GO GO:0005886; C:plasma membrane XX FT None XX Size: 143-152; Related: None; Template: P72358; Scope: Bacteria; Bacillales Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: None XX # Revision 1.17 2019/11/19 //