AC   MF_01147;
DC   Protein; auto
TR   HAMAP; MF_01147; -; 1; level=0
XX
Names: Lgt
XX
ID   LGT
DE   RecName: Full=Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase;
DE            EC=2.5.1.145;
GN   Name=lgt;
XX
CC   -!- FUNCTION: Catalyzes the transfer of the diacylglyceryl group from
CC       phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine
CC       of a prolipoprotein, the first step in the formation of mature
CC       lipoproteins.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-
CC         cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-
CC         cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate;
CC         Xref=Rhea:RHEA:56712, Rhea:RHEA-COMP:14679, Rhea:RHEA-COMP:14680,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29950, ChEBI:CHEBI:57685,
CC         ChEBI:CHEBI:64716, ChEBI:CHEBI:140658; EC=2.5.1.145;
CC   -!- PATHWAY: Protein modification; lipoprotein biosynthesis (diacylglyceryl
CC       transfer).
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the Lgt family.
XX
DR   Pfam; PF01790; LGT; 1; trigger=no
DR   NCBIfam; TIGR00544; lgt; 1; trigger=no
DR   PROSITE; PS01311; LGT; 1; trigger=no
DR   General; Transmembrane; -; 5-9; trigger=yes
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case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Membrane
KW   Transferase
KW   Transmembrane
KW   Transmembrane helix
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GO   GO:0008961; F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity
GO   GO:0042158; P:lipoprotein biosynthetic process
GO   GO:0005886; C:plasma membrane
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FT   From: LGT_ECOLI (P60955)
FT   BINDING         143
FT                   /ligand="1,2-diacyl-sn-glycero-3-phospho-(1'-sn-
FT                   glycerol)"
FT                   /ligand_id="ChEBI:CHEBI:64716"
FT   Condition: R
XX
Size: 243-492;
Related: None;
Template: Q2G044; P60959;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in BACC1, CLOPE, STRCO
Plasmid: in BACC1, PAEAT
Comments: None
XX
# Revision 1.37 2023/06/01
//