AC   MF_01148;
DC   Protein; auto
TR   HAMAP; MF_01148; -; 1; level=0
XX
Names: Lnt
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ID   LNT
DE   RecName: Full=Apolipoprotein N-acyltransferase;
DE            Short=ALP N-acyltransferase;
DE            EC=2.3.1.269;
GN   Name=lnt;
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CC   -!- FUNCTION: Catalyzes the phospholipid dependent N-acylation of the N-
CC       terminal cysteine of apolipoprotein, the last step in lipoprotein
CC       maturation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-
CC         cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) +
CC         N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein];
CC         Xref=Rhea:RHEA:48228, Rhea:RHEA-COMP:14681, Rhea:RHEA-COMP:14684,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:136912, ChEBI:CHEBI:140656,
CC         ChEBI:CHEBI:140657, ChEBI:CHEBI:140660; EC=2.3.1.269;
CC   -!- PATHWAY: Protein modification; lipoprotein biosynthesis (N-acyl
CC       transfer).
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the CN hydrolase family. Apolipoprotein N-
CC       acyltransferase subfamily.
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DR   Pfam; PF00795; CN_hydrolase; 1; trigger=no
DR   NCBIfam; TIGR00546; Lnt; 1; trigger=no
DR   PROSITE; PS50263; CN_HYDROLASE; 1; trigger=yes
DR   General; Transmembrane; -; 6-8; trigger=yes
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KW   Transferase
KW   Acyltransferase
KW   Transmembrane
KW   Membrane
KW   Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Transmembrane helix
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GO   GO:0016410; F:N-acyltransferase activity
GO   GO:0042158; P:lipoprotein biosynthetic process
GO   GO:0005886; C:plasma membrane
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FT   None
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Size: 400-595;
Related: None;
Template: P23930; Q8FJY4;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: <PPM synthase>
Duplicate: in LEPIN, TREDE, TREPA
Plasmid: None
Comments: In some Mycobacteria present as a fusion protein with PPM
 synthase (M.tuberculosis and M.bovis).
XX
# Revision 1.25 2023/06/01
//