AC   MF_01164;
DC   Protein; auto
TR   HAMAP; MF_01164; -; 1; level=0
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Names: ArnC_transfer
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ID   ARNC
DE   RecName: Full=Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase;
DE            EC=2.4.2.53;
DE   AltName: Full=Undecaprenyl-phosphate Ara4FN transferase;
DE            Short=Ara4FN transferase;
GN   Name=arnC;
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CC   -!- FUNCTION: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose
CC       from UDP to undecaprenyl phosphate. The modified arabinose is attached
CC       to lipid A and is required for resistance to polymyxin and cationic
CC       antimicrobial peptides.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=di-trans,octa-cis-undecaprenyl phosphate + UDP-4-deoxy-4-
CC         formamido-beta-L-arabinose = 4-deoxy-4-formamido-alpha-L-
CC         arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + UDP;
CC         Xref=Rhea:RHEA:27722, ChEBI:CHEBI:58223, ChEBI:CHEBI:58709,
CC         ChEBI:CHEBI:58909, ChEBI:CHEBI:60392; EC=2.4.2.53;
CC   -!- PATHWAY: Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose
CC       undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose
CC       undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose
CC       and undecaprenyl phosphate: step 1/2.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis.
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
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DR   Pfam; PF00535; Glycos_transf_2; 1; trigger=no
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
DR   General; Transmembrane; -; 2; trigger=yes
DR   ADD_TOPO_DOMAIN; Cytoplasmic; -; 2; trigger=yes
DR   ADD_TOPO_DOMAIN; Periplasmic; -; 1; trigger=yes
else
DR   General; Transmembrane; -; 2; trigger=yes
end case
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KW   Antibiotic resistance
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Glycosyltransferase
KW   Lipid A biosynthesis
KW   Lipid biosynthesis
KW   Lipid metabolism
KW   Lipopolysaccharide biosynthesis
KW   Membrane
KW   Transferase
KW   Transmembrane
KW   Transmembrane helix
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GO   GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups
GO   GO:0009245; P:lipid A biosynthetic process
GO   GO:0005886; C:plasma membrane
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FT   None
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Size: 322-341;
Related: None;
Template: P77757;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.34 2019/11/19
//