AC   MF_01165;
DC   Protein; auto
TR   HAMAP; MF_01165; -; 1; level=0
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Names: ArnT_transfer
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ID   ARNT
DE   RecName: Full=Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase;
DE            EC=2.4.2.43;
DE   AltName: Full=4-amino-4-deoxy-L-arabinose lipid A transferase;
DE   AltName: Full=Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase;
DE   AltName: Full=Undecaprenyl phosphate-alpha-L-Ara4N transferase;
GN   Name=arnT;
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CC   -!- FUNCTION: Catalyzes the transfer of the L-Ara4N moiety of the
CC       glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The
CC       modified arabinose is attached to lipid A and is required for
CC       resistance to polymyxin and cationic antimicrobial peptides.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-
CC         undecaprenyl phosphate + lipid IVA = lipid IIA + di-trans,octa-cis-
CC         undecaprenyl phosphate.; EC=2.4.2.43;
CC   -!- PATHWAY: Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-
CC       arabinose-lipid A biosynthesis.
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 83 family.
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DR   Pfam; PF02366; PMT; 1; trigger=no
DR   General; Transmembrane; -; 10-13; trigger=yes
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case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Glycosyltransferase
KW   Lipid A biosynthesis
KW   Lipid biosynthesis
KW   Lipid metabolism
KW   Lipopolysaccharide biosynthesis
KW   Membrane
KW   Transferase
KW   Transmembrane
KW   Transmembrane helix
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GO   GO:0016740; F:transferase activity
GO   GO:0009245; P:lipid A biosynthetic process
GO   GO:0005886; C:plasma membrane
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FT   None
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Size: 533-583;
Related: None;
Template: P76473; O52327;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in PROMH, PSEF5, PSEPF, SODGM
Plasmid: None
Comments: None
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# Revision 1.31 2022/04/28
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