AC   MF_01174;
DC   Protein; auto
TR   HAMAP; MF_01174; -; 1; level=0
XX
Names: Aldedh_AstD
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ID   ASTD
DE   RecName: Full=N-succinylglutamate 5-semialdehyde dehydrogenase;
DE            EC=1.2.1.71;
DE   AltName: Full=Succinylglutamic semialdehyde dehydrogenase;
DE            Short=SGSD;
GN   Name=astD;
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CC   -!- FUNCTION: Catalyzes the NAD-dependent reduction of succinylglutamate
CC       semialdehyde into succinylglutamate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) = 2 H(+)
CC         + N-succinyl-L-glutamate + NADH; Xref=Rhea:RHEA:10812,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57540,
CC         ChEBI:CHEBI:57945, ChEBI:CHEBI:58520, ChEBI:CHEBI:58763; EC=1.2.1.71;
CC   -!- PATHWAY: Amino-acid degradation; L-arginine degradation via AST
CC       pathway; L-glutamate and succinate from L-arginine: step 4/5.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family. AstD
CC       subfamily.
XX
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1; trigger=no
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1; trigger=no
DR   Pfam; PF00171; Aldedh; 1; trigger=no
DR   NCBIfam; TIGR03240; arg_catab_astD; 1; trigger=no
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KW   Arginine metabolism
KW   NAD
KW   Oxidoreductase
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GO   GO:0016491; F:oxidoreductase activity
GO   GO:0019544; P:arginine catabolic process to glutamate
XX
FT   From: ASTD_ECOLI (P76217)
FT   BINDING         220..225
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT   ACT_SITE        243
FT   Condition: E
FT   ACT_SITE        277
FT   Condition: C
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Size: 471-505;
Related: None;
Template: P76217;
Scope:
 Bacteria; Pseudomonadota
Fusion:
 Nter: None
 Cter: None
Duplicate: in CAUVC, PSET1, SHEDO
Plasmid: None
Comments: None
XX
# Revision 1.21 2023/06/01
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