AC   MF_01176;
DC   Protein; auto
TR   HAMAP; MF_01176; -; 1; level=0
XX
Names: HTH_type_IscR
XX
ID   ISCR
DE   RecName: Full=HTH-type transcriptional regulator IscR;
GN   Name=iscR;
XX
CC   -!- FUNCTION: Regulates the transcription of several operons and genes
CC       involved in the biogenesis of Fe-S clusters and Fe-S-containing
CC       proteins.
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC       Note=Binds 1 [2Fe-2S] cluster.;
end case
XX
DR   PROSITE; PS01332; HTH_RRF2_1; 1; trigger=no
DR   PROSITE; PS51197; HTH_RRF2_2; 1; trigger=yes
DR   Pfam; PF02082; Rrf2; 1; trigger=no
DR   NCBIfam; TIGR02010; IscR; 1; trigger=no
DR   NCBIfam; TIGR00738; Rrf2_super; 1; trigger=no
XX
case <FTGroup:1>
KW   2Fe-2S
end case
KW   Activator
KW   DNA-binding
case <FTGroup:1>
KW   Iron
KW   Iron-sulfur
KW   Metal-binding
end case
KW   Repressor
KW   Transcription
KW   Transcription regulation
XX
GO   GO:0003690; F:double-stranded DNA binding
case <FTGroup:1>
GO   GO:0005506; F:iron ion binding
end case
GO   GO:0003700; F:DNA-binding transcription factor activity
GO   GO:0006355; P:regulation of DNA-templated transcription
XX
FT   From: ISCR_ECOLI (P0AGK8)
FT   BINDING         92
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT   Group: 1; Condition: C
FT   BINDING         98
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT   Group: 1; Condition: C
FT   BINDING         104
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT   Group: 1; Condition: C
XX
Size: 162-173;
Related: None;
Template: P0AGK8;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.24 2023/06/01
//