AC   MF_01192;
DC   Protein; auto
TR   HAMAP; MF_01192; -; 1; level=0
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Names: Xni
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ID   XNI
DE   RecName: Full=Flap endonuclease Xni;
DE            Short=FEN;
DE            EC=3.1.-.-;
GN   Name=xni; Synonyms=ygdG;
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CC   -!- FUNCTION: Has flap endonuclease activity. During DNA replication, flap
CC       endonucleases cleave the 5'-overhanging flap structure that is
CC       generated by displacement synthesis when DNA polymerase encounters the
CC       5'-end of a downstream Okazaki fragment.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC       Note=Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct
CC       interaction with the protein, the other interactions are indirect.;
CC   -!- COFACTOR:
CC       Name=K(+); Xref=ChEBI:CHEBI:29103;
CC       Note=Binds 1 K(+) per subunit. The potassium ion strongly increases the
CC       affinity for DNA.;
CC   -!- SIMILARITY: Belongs to the Xni family.
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DR   Pfam; PF01367; 5_3_exonuc; 1; trigger=yes
DR   Pfam; PF02739; 5_3_exonuc_N; 1; trigger=no
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KW   DNA-binding
KW   Endonuclease
KW   Hydrolase
KW   Magnesium
KW   Metal-binding
KW   Nuclease
KW   Potassium
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GO   GO:0000287; F:magnesium ion binding
GO   GO:0003677; F:DNA binding
GO   GO:0017108; F:5'-flap endonuclease activity
GO   GO:0030955; F:potassium ion binding
GO   GO:0033567; P:DNA replication, Okazaki fragment processing
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FT   From: XNI_ECOLI (P38506)
FT   REGION          184..189
FT                   /note="Interaction with DNA"
FT   BINDING         104
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
FT   BINDING         171
FT                   /ligand="K(+)"
FT                   /ligand_id="ChEBI:CHEBI:29103"
FT   Condition: [LIMF]
FT   BINDING         172
FT                   /ligand="K(+)"
FT                   /ligand_id="ChEBI:CHEBI:29103"
FT   Optional; Condition: A
FT   BINDING         180
FT                   /ligand="K(+)"
FT                   /ligand_id="ChEBI:CHEBI:29103"
FT   Optional; Condition: P
FT   BINDING         182
FT                   /ligand="K(+)"
FT                   /ligand_id="ChEBI:CHEBI:29103"
FT   Condition: [VI]
FT   BINDING         185
FT                   /ligand="K(+)"
FT                   /ligand_id="ChEBI:CHEBI:29103"
FT   Condition: [IV]
XX
Size: 250-290;
Related: None;
Template: P38506;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.15 2022/11/19
//