AC   MF_01203;
DC   Protein; auto
TR   HAMAP; MF_01203; -; 1; level=0
XX
Names: CLC_ClcB
XX
case <OC:Enterobacterales>
ID   CLCB
DE   RecName: Full=Voltage-gated ClC-type chloride channel ClcB;
GN   Name=clcB;
else
ID   CLCL
DE   RecName: Full=Putative chloride channel protein ClcB-like;
end case
XX
case <OC:Enterobacterales>
CC   -!- FUNCTION: Probably acts as an electrical shunt for an outwardly-
CC       directed proton pump that is linked to amino acid decarboxylation, as
CC       part of the extreme acid resistance (XAR) response.
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family. ClcB
CC       subfamily.
XX
DR   Pfam; PF00654; Voltage_CLC; 1; trigger=no
DR   PRINTS; PR00762; CLCHANNEL; 1; trigger=no
DR   General; Transmembrane; -; 9-11; trigger=yes
XX
KW   Transport
KW   Ion transport
KW   Ion channel
KW   Voltage-gated channel
KW   Chloride channel
KW   Chloride
KW   Membrane
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Cell membrane
KW   Transmembrane
KW   Transmembrane helix
XX
GO   GO:0005247; F:voltage-gated chloride channel activity
GO   GO:0006821; P:chloride transport
GO   GO:0005886; C:plasma membrane
XX
FT   None
XX
Size: 414-461;
Related: None;
Template: P76175;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: in RALN1
Comments: In view of recent findings for ClcA in E.coli, ClcB may also be an exchange
 transporter and not a voltage-gated channel.
XX
# Revision 1.35 2023/11/28
//