AC   MF_01204;
DC   Protein; auto
TR   HAMAP; MF_01204; -; 1; level=0
XX
Names: Oxidoreductase_RutE_HadB
XX
case <OC:Enterobacterales>
ID   RUTE
DE   RecName: Full=Probable malonic semialdehyde reductase RutE;
DE            EC=1.1.1.298;
GN   Name=rutE;
end case
case not <OC:Enterobacterales>
ID   Ynnn
DE   RecName: Full=Putative NADH dehydrogenase/NAD(P)H nitroreductase <locus_tag>;
DE            EC=1.-.-.-;
end case
XX
case <OC:Enterobacterales>
CC   -!- FUNCTION: May reduce toxic product malonic semialdehyde to 3-
CC       hydroxypropionic acid, which is excreted.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3-hydroxypropanoate + NADP(+) = 3-oxopropanoate + H(+) +
CC         NADPH; Xref=Rhea:RHEA:26438, ChEBI:CHEBI:15378, ChEBI:CHEBI:16510,
CC         ChEBI:CHEBI:33190, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349;
CC         EC=1.1.1.298;
end case
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
case <OC:Escherichia> or <OC:Shigella>
CC   -!- INDUCTION: Up-regulated by the nitrogen regulatory protein C (NtrC also
CC       called GlnG) and repressed by RutR.
end case
CC   -!- SIMILARITY: Belongs to the nitroreductase family. HadB/RutE subfamily.
XX
DR   Pfam; PF00881; Nitroreductase; 1; trigger=no
XX
KW   Oxidoreductase
KW   NAD
KW   NADP
KW   Flavoprotein
KW   FMN
XX
case <OC:Enterobacterales>
GO   GO:0035527; F:3-hydroxypropionate dehydrogenase (NADP+) activity
GO   GO:0006212; P:uracil catabolic process
GO   GO:0019740; P:nitrogen utilization
end case
case not <OC:Enterobacterales>
GO   GO:0016491; F:oxidoreductase activity
end case
XX
FT   None
XX
Size: 195-202;
Related: None;
Template: P75894;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in STRCO
Plasmid: None
Comments: The rut operon for pyrimidine utilization seems to be absent in salmonellae.
XX
# Revision 1.31 2021/01/12
//