AC MF_01244; DC Protein; auto TR HAMAP; MF_01244; -; 1; level=0 XX Names: Arch_DHQ_synthase XX case ID DHQS DE RecName: Full=3-dehydroquinate synthase; DE Short=DHQ synthase; DE EC=1.4.1.24; DE AltName: Full=3-dehydroquinate synthase II; GN Name=aroB'; end case case ID DHQSH DE RecName: Full=3-dehydroquinate synthase homolog; DE EC=1.4.1.-; end case XX case CC -!- FUNCTION: Catalyzes the oxidative deamination and cyclization of 2- CC amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- CC dehydroquinate (DHQ), which is fed into the canonical shikimic pathway CC of aromatic amino acid biosynthesis. CC -!- CATALYTIC ACTIVITY: CC Reaction=2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) CC = 3-dehydroquinate + H(+) + NADH + NH4(+); Xref=Rhea:RHEA:25956, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, CC ChEBI:CHEBI:32364, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, CC ChEBI:CHEBI:58859; EC=1.4.1.24; end case CC -!- SIMILARITY: Belongs to the archaeal-type DHQ synthase family. XX DR Pfam; PF01959; DHQS; 1; trigger=no XX KW Amino-acid biosynthesis KW Aromatic amino acid biosynthesis KW NAD KW Oxidoreductase XX GO GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor GO GO:0051287; F:NAD binding GO GO:0009073; P:aromatic amino acid family biosynthetic process XX FT None XX Size: 323-402; Related: None; Template: Q58646; Q6M1B0; Scope: Bacteria; Aquificae Archaea Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: None XX # Revision 1.20 2019/11/19 //