AC   MF_01271;
DC   Protein; auto
TR   HAMAP; MF_01271; -; 1; level=0
XX
Names: GlcNAc_kinase
XX
ID   NAGK
DE   RecName: Full=N-acetyl-D-glucosamine kinase;
DE            EC=2.7.1.59;
DE   AltName: Full=GlcNAc kinase;
GN   Name=nagK;
XX
CC   -!- FUNCTION: Catalyzes the phosphorylation of N-acetyl-D-glucosamine
CC       (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + N-acetyl-D-glucosamine = ADP + H(+) + N-acetyl-D-
CC         glucosamine 6-phosphate; Xref=Rhea:RHEA:17417, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:57513, ChEBI:CHEBI:456216,
CC         ChEBI:CHEBI:506227; EC=2.7.1.59;
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan recycling.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
XX
DR   PROSITE; PS01125; ROK; 1; trigger=no
DR   Pfam; PF00480; ROK; 1; trigger=no
XX
KW   ATP-binding
KW   Carbohydrate metabolism
KW   Kinase
KW   Nucleotide-binding
KW   Transferase
case <FTGroup:1>
KW   Metal-binding
KW   Zinc
end case
XX
GO   GO:0005524; F:ATP binding
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
GO   GO:0045127; F:N-acetylglucosamine kinase activity
GO   GO:0006044; P:N-acetylglucosamine metabolic process
GO   GO:0009254; P:peptidoglycan turnover
XX
FT   From: NAGK_ECOLI (P75959)
FT   BINDING         4..11
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   BINDING         133..140
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   BINDING         157
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: H
FT   BINDING         177
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: C
FT   BINDING         179
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: C
FT   BINDING         184
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: C
XX
Size: 256-305;
Related: None;
Template: P75959; Q8ZPZ9;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: NagK sequences from YERPE, YERPA and YERPN (but not YERPS) are shorter,
 due to a probable natural frameshift in the C-terminus; they are not included in
 alignment.
XX
# Revision 1.15 2022/11/19
//