AC   MF_01280;
DC   Protein; auto
TR   HAMAP; MF_01280; -; 1; level=0
XX
Names: Diacylglyc_glucosyltr
XX
ID   UGTP
case <OC:Bacillus>
DE   RecName: Full=Processive diacylglycerol beta-glucosyltransferase;
DE            EC=2.4.1.315;
DE   AltName: Full=Beta-diglucosyldiacylglycerol synthase;
DE            Short=Beta-DGS;
DE            Short=DGlcDAG synthase;
DE            Short=Glc2-DAG synthase;
DE   AltName: Full=Beta-gentiobiosyldiacylglycerol synthase;
DE   AltName: Full=Beta-monoglucosyldiacylglycerol synthase;
DE            Short=Beta-MGS;
DE            Short=MGlcDAG synthase;
DE   AltName: Full=Beta-triglucosyldiacylglycerol synthase;
DE            Short=TGlcDAG synthase;
DE   AltName: Full=Diglucosyl diacylglycerol synthase (1,6-linking);
DE   AltName: Full=Glucosyl-beta-1,6-glucosyldiacylglycerol synthase;
DE   AltName: Full=UDP glucosyltransferase;
DE   AltName: Full=UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase;
else
DE   RecName: Full=Processive diacylglycerol beta-glucosyltransferase;
DE            EC=2.4.1.315;
DE   AltName: Full=Beta-diglucosyldiacylglycerol synthase;
DE            Short=Beta-DGS;
DE            Short=DGlcDAG synthase;
DE            Short=Glc2-DAG synthase;
DE   AltName: Full=Beta-gentiobiosyldiacylglycerol synthase;
DE   AltName: Full=Beta-monoglucosyldiacylglycerol synthase;
DE            Short=Beta-MGS;
DE            Short=MGlcDAG synthase;
DE   AltName: Full=Diglucosyl diacylglycerol synthase (1,6-linking);
DE   AltName: Full=Glucosyl-beta-1,6-glucosyldiacylglycerol synthase;
DE   AltName: Full=UDP glucosyltransferase;
DE   AltName: Full=UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase;
end case
GN   Name=ugtP;
XX
case <OC:Bacillus>
CC   -!- FUNCTION: Processive glucosyltransferase involved in the biosynthesis
CC       of both the bilayer- and non-bilayer-forming membrane glucolipids. Is
CC       able to successively transfer up to three glucosyl residues to
CC       diacylglycerol (DAG), thereby catalyzing the formation of beta-
CC       monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol),
CC       beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-
CC       glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-
CC       (beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-
CC       glucopyranosyl)-1,2-diacyl-sn-glycerol). Beta-diglucosyl-DAG is the
CC       predominant glycolipid found in Bacillales and is also used as a
CC       membrane anchor for lipoteichoic acid (LTA).
else
CC   -!- FUNCTION: Processive glucosyltransferase involved in the biosynthesis
CC       of both the bilayer- and non-bilayer-forming membrane glucolipids. Is
CC       able to successively transfer two glucosyl residues to diacylglycerol
CC       (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-
CC       (beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-diglucosyl-DAG
CC       (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-
CC       sn-glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found
CC       in Bacillales and is also used as a membrane anchor for lipoteichoic
CC       acid (LTA).
end case
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + UDP-
CC         alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-
CC         glycerol + H(+) + UDP; Xref=Rhea:RHEA:39031, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:58223, ChEBI:CHEBI:58885, ChEBI:CHEBI:75799,
CC         ChEBI:CHEBI:76264; EC=2.4.1.315;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-
CC         3-O-(beta-D-glucopyranosyl)-sn-glycerol + H(+) + UDP;
CC         Xref=Rhea:RHEA:17285, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815,
CC         ChEBI:CHEBI:58223, ChEBI:CHEBI:58885, ChEBI:CHEBI:75799;
case <OC:Bacillus>
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol +
CC         UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-
CC         (1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP; Xref=Rhea:RHEA:39027,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885,
CC         ChEBI:CHEBI:76264, ChEBI:CHEBI:76265; EC=2.4.1.315;
end case
CC   -!- PATHWAY: Glycolipid metabolism; diglucosyl-diacylglycerol biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell membrane.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 28 family. UgtP
CC       subfamily.
XX
DR   Pfam; PF00534; Glycos_transf_1; 1; trigger=no
DR   Pfam; PF06925; MGDG_synth; 1; trigger=no
DR   Pfam; PF04101; Glyco_tran_28_C; 1; trigger=no
XX
KW   Carbohydrate metabolism
KW   Cell membrane
KW   Glycosyltransferase
KW   Lipid biosynthesis
KW   Lipid metabolism
KW   Membrane
KW   Transferase
XX
GO   GO:0035251; F:UDP-glucosyltransferase activity
GO   GO:0047228; F:1,2-diacylglycerol 3-glucosyltransferase activity
GO   GO:0009247; P:glycolipid biosynthetic process
GO   GO:0070395; P:lipoteichoic acid biosynthetic process
XX
FT   None
XX
Size: 382-391;
Related: None;
Template: P54166; Q5HH69; Q2FZP7;
Scope:
 Bacteria; Bacillales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.13 2019/11/19
//